Overview: the neurochemistry of respiratory control.

Respiratory Physiology & Neurobiology
Donald R McCrimmonGeorge F Alheid

Abstract

This special issue of Respiratory Physiology and Neurobiology surveys a broad range of topics focused on the neurochemical control of breathing. A variety of approaches have integrated the neurochemistry of breathing with the physiology of individual neurons, with the neuroanatomy of brainstem and forebrain respiratory circuits, and with the clinical pathology of respiratory disorders all of which has been fueled by the ongoing explosion of information in the molecular biology of the nervous system. Accordingly, substantial progress has identified neurotransmitters, neuromodulators, receptors, signaling cascades, trophic factors, hormones, and genes mediating normal and pathological breathing. Dynamic changes in the neurochemistry of breathing are addressed with respect to brainstem development, environmental challenges such as intermittent or chronic hypoxia, and as a function of the sleep-wake cycle. Respiratory disruption has also been identified in an increasing variety of genetic-based disorders and remarkable progress has been made in determining the affected genes and their mutations that negatively impact respiration.

References

Apr 9, 2008·Respiratory Physiology & Neurobiology·Peter M Lalley
Jun 3, 2008·Respiratory Physiology & Neurobiology·Leszek Kubin, Denys V Volgin
Jun 6, 2008·Respiratory Physiology & Neurobiology·David D Kline
Jun 7, 2008·Respiratory Physiology & Neurobiology·Michael Ogier, David M Katz
Jun 14, 2008·Respiratory Physiology & Neurobiology·Luciane H GargaglioniLuiz Guilherme S Branco
Jun 28, 2008·Respiratory Physiology & Neurobiology·Eckehard A StuthEdward J Zuperku
Jul 4, 2008·Respiratory Physiology & Neurobiology·Matthew R Hodges, George B Richerson
Jul 8, 2008·Respiratory Physiology & Neurobiology·Atsushi Doi, Jan-Marino Ramirez
Jul 16, 2008·Respiratory Physiology & Neurobiology·Richard L Horner
Jul 19, 2008·Respiratory Physiology & Neurobiology·Jean-Charles Viemari
Jul 19, 2008·Respiratory Physiology & Neurobiology·Francis J Golder
Aug 5, 2008·Respiratory Physiology & Neurobiology·Jorge Gallego, Stéphane Dauger
Aug 12, 2008·Respiratory Physiology & Neurobiology·Jayasri NanduriNanduri R Prabhakar
Aug 12, 2008·Respiratory Physiology & Neurobiology·P M MacFarlaneG S Mitchell
Aug 16, 2008·Respiratory Physiology & Neurobiology·Gaspard MontandonAida Bairam
Aug 19, 2008·Respiratory Physiology & Neurobiology·George F Alheid, Donald R McCrimmon
Aug 19, 2008·Respiratory Physiology & Neurobiology·Paul M Pilowsky
Aug 19, 2008·Respiratory Physiology & Neurobiology·Carlos B Mantilla, Gary C Sieck
Sep 13, 2008·Respiratory Physiology & Neurobiology·Stephen R ReevesDavid Gozal

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Citations

Aug 26, 2010·The Journal of Comparative Neurology·Patrice G GuyenetDouglas A Bayliss
Sep 22, 2011·The Journal of Comparative Neurology·Genrieta BochorishviliPatrice G Guyenet

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