PMID: 11913844Mar 27, 2002Paper

Overwear of contact lenses: increased severity of clinical signs as a function of protein adsorption

Optometry and Vision Science : Official Publication of the American Academy of Optometry
Langis Michaud, Claude J Giasson

Abstract

This study compared the clinical behavior of disposable and frequent replacement Acuvue and 1-Day contact lenses. Each type of lens was worn on one eye according to the schedule recommended by the manufacturer, and on the other eye for a longer period of time, up to 30 days in length. Both type of lenses were prescribed on a daily-wear basis. The amount of protein collected from the lenses was measured using two spectrophotometric protein assays. Visual acuity and comfort, along with several other clinical signs, were classified according to Cornea and Contact Lens Research Unit (CCLRU) scales, and possible associations between each of these signs and the amount of protein extracted from the lenses was tested. A comparison between the lens worn on the compliant eye with the lens worn on the noncompliant eye allowed us to measure the impact of overwear on ocular health and subjective clinical findings. After four months of study, the overwear of Acuvue and 1-Day lenses significantly increased the amount of protein bound on the contact lenses, as well as the severity of upper conjunctival papillae, upper lid conjunctival hyperemia, and limbal congestion. Even if reduced values for visual acuity and noninvasive break-up time (NIBU...Continue Reading

References

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Citations

Nov 28, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Sin Wan CheungMarion H Edwards
Oct 17, 2007·The Ocular Surface·Christine W Sindt, Reid A Longmuir
Aug 2, 2011·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Charles W McMonnies
Jul 30, 2011·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Charles W McMonnies
Nov 3, 2010·Optometry : Journal of the American Optometric Association·Karen K YeungBarry A Weissman
Nov 3, 2009·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·DeGaulle I Chigbu
Jan 9, 2007·Optometry : Journal of the American Optometric Association·Patrick CaronLangis Michaud
Jul 12, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·J M González-MéijomeM A Parafita
Oct 12, 2012·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Nathan Efron
Mar 31, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·James S WolffsohnUNKNOWN British Universities Committee of Contact Lens Educators (BUCCLE)
Jun 19, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Kathryn A DumbletonLyndon W Jones

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