Overweight and obesity are associated with lower vitamin D status in Canadian children and adolescents

Paediatrics & Child Health
Linda S Greene-FinestoneSusan J Whiting

Abstract

There is evidence that 25-hydroxyvitamin D levels are lower in overweight and obese youth. This study examined the relationship between weight status and 25-hydroxyvitamin D, while controlling for confounders, in Canadian youth. Plasma 25-hydroxyvitamin D from subjects aged 6 to 17 years from the Canadian Health Measures Survey cycles 1 (2007 to 2009) and 2 (2009 to 2011) was used. Sex-specific multiple linear regression and logistic regressions examined the relationship of overweight and obesity (body mass index ≥ 85th percentile) with 25-hydroxyvitamin D levels and the odds of 25-hydroxyvitamin D <40 nmol/L and <50 nmol/L. The prevalence of risk of vitamin D deficiency (25-hydroxyvitamin D < 30 nmol/L) was 6% (95% confidence interval [CI] 3.26% to 10.12%). Vitamin D inadequacy, estimated by levels <40 nmol/L, was 15% (95% CI 10.34% to 20.39%; 19% [95% CI 13.1 to 25.6] for teenagers). Seventy per cent (95% CI 63.59 to 75.17) had levels >50 nmol/L, consistent with achieving the Recommended Dietary Allowance. In adjusted analyses, overweight/obesity (1/3 of subjects) was independently associated with lower 25-hydroxyvitamin D for both sexes after adjustment for age, race, income, season, vitamin D supplementation and daily milk ...Continue Reading

References

Sep 1, 2000·The American Journal of Clinical Nutrition·J WortsmanM F Holick
Dec 8, 2005·Canadian Journal of Dietetic Practice and Research : a Publication of Dietitians of Canada = Revue Canadienne De La Pratique Et De La Recherche En Diététique : Une Publication Des Diététistes Du Canada·Linda Gillis, Aubrey Gillis
Jul 20, 2007·The New England Journal of Medicine·Michael F Holick
Aug 12, 2008·Journal of the American College of Nutrition·Miriam BlumBess Dawson-Hughes
Apr 20, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Hassanali VatanparastSusan J Whiting
Oct 12, 2010·The American Journal of Clinical Nutrition·Diane Gilbert-DiamondEduardo Villamor
Apr 20, 2011·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Zeev HarelDalia Harel
Jan 17, 2012·Clinical Chemistry·Annemieke C HeijboerMadelon M Buijs
Jun 22, 2012·Public Health Nutrition·Mercedes de OnisUNKNOWN WHO Multicentre Growth Reference Study Group
Oct 26, 2012·The American Journal of Clinical Nutrition·Christine L TaylorElizabeth A Yetley
Dec 26, 2012·Pediatrics·Christy B TurerGlenn Flores
Jun 8, 2013·Preventing Chronic Disease·Bibiana García-BailoAlaa Badawi
Aug 7, 2013·Journal of the Academy of Nutrition and Dietetics·Lauren E AuJennifer M Sacheck
Nov 2, 2014·The Proceedings of the Nutrition Society·L Kirsty Pourshahidi
Mar 31, 2015·Molecular and Cellular Endocrinology·Norman K Pollock
Mar 1, 2013·Bone Research·Francisco J A de Paula, Clifford J Rosen
Oct 2, 2015·The American Journal of Clinical Nutrition·Kurtis SarafinStephen Pj Brooks
Jun 24, 2016·Pediatrics·Gustavo CedielRicardo Uauy

❮ Previous
Next ❯

Citations

Jul 4, 2019·Nutrients·Emanuela A GrecoSilvia Migliaccio
Oct 28, 2019·Reviews in Endocrine & Metabolic Disorders·Evelyn FerriBeatrice Arosio
May 16, 2019·Journal of Obesity & Metabolic Syndrome·Jung Eun ParkYoun-Soo Cha
Jan 21, 2021·International Journal of General Medicine·Di WangChunlin Wang
Oct 3, 2021·Scientific Reports·Živa RadulovićNataša Marčun Varda
Sep 14, 2021·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Stephen P J BrooksHope A Weiler

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.