PMID: 7084807Jul 1, 1982Paper

Overwhelming pneumococcal septicaemia in a patient with ulcerative colitis and splenic atrophy

Gut
K J FosterR M Abbott

Abstract

This report describes a young woman with ulcerative colitis who developed rapidly fatal pneumococcal septicaemia. Necropsy revealed splenic atrophy. This case supports the hypothesis that splenic atrophy might contribute to the morbidity of ulcerative colitis. The occurrence of splenic atrophy in ulcerative colitis is now well established. Splenic atrophy from other causes has been associated with severe bacterial infections, often pneumococcal. It has been suggested that splenic atrophy is most severe when ulcerative colitis is active and may contribute to postoperative morbidity. This case documents overwhelming septicaemia in a patient with splenic atrophy whose colitis was in remission.

Citations

Apr 1, 1997·Alcoholism, Clinical and Experimental Research·G R CorazzaG Gasbarrini
Nov 13, 1982·British Medical Journal·A Ferguson
Feb 1, 1995·Gut·A F Muller, P J Toghill
Mar 30, 2013·World Journal of Gastroenterology : WJG·Elisa CarreraElena Garrido
Jul 5, 2006·The American Journal of Gastroenterology·Gil Y MelmedEric A Vasiliauskas
Aug 10, 2005·The American Journal of Gastroenterology·Antonio Di SabatinoRita Carsetti
Oct 1, 1983·Scottish Medical Journal·K R Lees, C G Isles
Apr 10, 2020·Frontiers in Immunology·Marco Vincenzo LentiAntonio Di Sabatino
Mar 18, 2011·Deutsches Ärzteblatt International·Niels TeichIngolf Schiefke

Related Concepts

Atrophic
Ulcerative Colitis
Pneumococcal Infections
Spleen
Pyemia

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