PMID: 9548186Apr 21, 1998Paper

Ovine placentome morphology: effect of high altitude, long-term hypoxia

Placenta
L Penninga, Lawrence D Longo

Abstract

The effect of high altitude, long-term hypoxaemia on placentome morphology in the sheep was examined using singleton and twin pregnant ewes. Normoxic twins had lower fetal and placental weights (3.7+/-0.2 kg and 215+/-26 g, respectively) than normoxic singleton fetuses (4.3+/-0.2 kg and 336+/-17 g, respectively). Fetal and placental weights were similar in normoxic singleton and high altitude (3820 m) hypoxic singleton fetuses (4.3+/-0.2 and 4.4+/-0.4 kg, 336+/-17 and 342+/-62 g, respectively). The distribution of placentome types was classified into four major categories (A-D) and for normoxic singletons was as follows: A=76+/-4, B=22+/-3, C=1+/-2, and D=1+/-1. Normoxic twins tended to have more type B (type A=63+/-10, B=33+/-8, C=2+/-1, and D=2+/-1). High altitude hypoxic singletons had significantly fewer type A (33+/-4) and more type B (50+/-3), C (10+/-7), D (7+/-1) placentomes than normoxic singletons. In addition, in the sea-level control group, five animals were found to be spontaneously hypoxic with a placentome distribution similar to that of the high altitude hypoxic fetuses. In conclusion, both high altitude, long-term hypoxia and low altitude spontaneous hypoxia lead to a significant change in placentome distributi...Continue Reading

References

Aug 1, 1978·Biology of Reproduction·D J Garvey, L D Longo
Jan 1, 1986·Biology of the Neonate·T J de GrauwW J Scott
Aug 1, 1969·Archives of Environmental Health·R Bason, C E Billings
Jan 1, 1966·Acta Anatomica·J Davies, W A Wimsatt
May 1, 1967·The Journal of Clinical Investigation·L D LongoR E Forster
Jan 1, 1984·Biology of the Neonate·J H ChangR Abbe
Dec 1, 1994·American Journal of Obstetrics and Gynecology·O S ReshetnikovaA P Milovanov
Jan 1, 1994·Experimental and Clinical Endocrinology·R Leiser, P Kaufmann
Jun 1, 1964·Journal of Reproduction and Fertility·G ALEXANDER

❮ Previous
Next ❯

Citations

Jul 31, 1998·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·L D Longo, W J Pearce
Oct 31, 2009·The International Journal of Developmental Biology·Ciprian P GheorgheLawrence D Longo
Sep 28, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C SteynM A Hanson
May 21, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·E M BeckettV Padmanabhan
Jan 13, 2015·Nutrients·Song ZhangJanna L Morrison
Jan 28, 2006·The Journal of Physiology·A L FowdenM Constancia
Feb 13, 2008·Journal of Neuroendocrinology·A L FowdenG J Burton
Apr 2, 2014·Glia·Stephen A Back, Paul A Rosenberg
Aug 4, 2015·The Journal of Physiology·Vicki L CliftonRobert J Bischof
Sep 2, 2003·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·Andrea MessUlrich Zeller
Sep 5, 2006·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Amanda E O'ConnellKaren J Gibson
May 14, 2016·Theriogenology·S BairagiL P Reynolds
Oct 1, 2016·Journal of Developmental Origins of Health and Disease·H DickinsonJ L Morrison
Jun 26, 2010·Experimental Biology and Medicine·Timothy R H RegnaultFrederick C Battaglia
Jan 2, 2009·Animal Reproduction Science·R E G RiciM A Miglino
Jul 27, 2014·Reproductive Sciences·Thorsten BraunJohn R G Challis
Jul 20, 2007·Reproductive Sciences·Takuji TomimatsuLawrence D Longo
Jul 20, 2007·Reproductive Sciences·Ciprian P GheorgheLawrence D Longo
Mar 31, 2004·Journal of the Society for Gynecologic Investigation·Toshiko ImamuraCharles A Ducsay
Dec 15, 2015·Physiological Reports·Kirsty L BrainDino A Giussani
May 3, 2018·Physiological Reviews·Charles A DucsayLubo Zhang
Sep 9, 2016·Physiological Reviews·Graham J BurtonKent L Thornburg
Jul 3, 2004·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ellen JensenMaureen Keller-Wood
Jan 15, 2002·American Journal of Physiology. Endocrinology and Metabolism·Frank H BloomfieldJane E Harding
Mar 29, 2013·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dan Rurak, Natalee W Bessette
Aug 2, 2017·Journal of Genetics·S Purnima SailasreeRakesh K Mishra
Aug 13, 1999·The American Journal of Physiology·A M LewisR D Gilbert
Nov 24, 1999·The American Journal of Physiology·J J Smolich, M D Esler
Jul 4, 2017·Zygote : the Biology of Gametes and Early Embryos·Ruoxin JiaFeng Wang
May 24, 2005·Reproduction, Fertility, and Development·V Ctor H ParraguezLuis A Raggi
Oct 26, 2012·Journal of Animal Science·D S van der LindenS A McCoard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.