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Oxidant-induced cytotoxicity: a challenge for metabolic modulation

Abstract

References

Association of poly(adenosine diphosphoribose) synthesis with DNA damage and repair in normal human lymphocytes

DNA strand break formation following exposure of bovine pulmonary artery and aortic endothelial cells to reactive oxygen products

Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase

Metabolic consequences of DNA damage: DNA damage induces alterations in glucose metabolism by activation of poly (ADP-ribose) polymerase

Alterations in deoxynucleoside triphosphate metabolism in DNA damaged cells: identification and consequences of poly(ADP-ribose) polymerase dependent and independent processes

Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells

Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes

Purification and characterization of human lymphoid poly(adenosine diphosphate ribose) polymerase

Poly(ADP-ribose) Polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis

Amplification of pyridine nucleotide pools in mitogen-stimulated human lymphocytes

Pathogenesis of the adult respiratory distress syndrome. Evidence of oxidant activity in bronchoalveolar lavage fluid

Citations

Oxidative stress and living cells

Acute pneumocyte injury, poly(ADP-ribose) polymerase activity, and pyridine nucleotide levels after in vitro exposure of murine lung slices to cyclophosphamide

Synthesis of poly(ADP-ribose) in asbestos treated rat pleural mesothelial cells in culture

DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite

3-aminobenzamide protects the mouse thymocytes in vitro from dexamethasone-mediated apoptotic cell death and cytolysis without changing DNA strand breakage

Role of poly(ADP-ribose)synthetase in inflammation

Protection from acetaminophen-induced liver damage by the synergistic action of low doses of the poly(ADP-ribose) polymerase-inhibitor nicotinamide and the antioxidant N-acetylcysteine or the amino acid L-methionine

Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion

Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma

Hemorrhagic shock in swine: nitric oxide and potassium sensitive adenosine triphosphate channel activation

Intestinal ischemia-reperfusion injury causes pulmonary endothelial cell ATP depletion

Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents

Poly(adenosine 5'-diphosphate) ribose polymerase activation as a cause of metabolic dysfunction in critical illness

DNA strand breaks in human nasal respiratory epithelium are induced upon exposure to urban pollution

Alteration of adenosine triphosphate and other nucleotides after sublethal oxidant injury to rat type II alveolar epithelial cells

Effect of PJ-34 PARP-inhibitor on rat liver microcirculation and antioxidant status

Nicotinamide increases systemic vascular resistance in ovine endotoxemia

Poly(ADP-ribose) polymerase activation by reactive nitrogen species--relevance for the pathogenesis of inflammation

NAD depletion after in vitro exposure of murine lung slices to bleomycin

DNA damage induced by peroxynitrite: subsequent biological effects

Role of the neutrophil in adult respiratory distress syndrome

Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells

Induction of fibronectin gene expression by transforming growth factor beta-1 is attenuated in bronchial epithelial cells by ADP-ribosyltransferase inhibitors

Lunotriquetral ligament properties: a comparison of three anatomic subregions

Evidence of nitric oxide synthase 2 activity in swine naturally infected with Actinobacillus pleuropneumoniae

Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices