Oxidation and wear of 100-Mrad cross-linked polyethylene shelf-aged for 30 years

Clinical Orthopaedics and Related Research
Hironobu OonishiShingo Masuda

Abstract

Some previous studies suggest that aging influences wear and oxidatively degraded nonsterilized ultra-high-molecular-weight polyethylene (UHMWPE) exhibits decreased wear resistance. We therefore asked whether shelf-aging storage conditions influenced degradation and wear resistance of gamma-irradiated UHMWPE. We examined oxidation and wear of 100-Mrad gamma-irradiated UHMWPE (100-Mrad polyethylene) cups shelf-aged for 30 years without (n=2) or with (n=2) packages. The oxidation index of the unpackaged 100-Mrad polyethylene surface (4) was higher than that of the packaged one (2.7). The packaged 100-Mrad polyethylene cup exhibited a high wear resistance with a steady wear rate of 0.5 mg/10(6) cycles. In contrast, the unpackaged 100-Mrad polyethylene exhibited an extremely high initial wear rate of 187.9 mg/10(6) cycles over the first 0.25 x 10(6) cycles with a subsequently reduced wear rate of 5 mg/10(6) cycles after 5 x 10(6) cycles. Packaging over long periods inhibits surface oxidation and maintains the wear resistance of gamma-irradiated UHMWPE cups.

References

Jul 1, 1971·Arthritis and Rheumatism·P S Treuhaft, D J MCCarty
Apr 30, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·H McKellopR Salovey
Jun 22, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·H A McKellopT Ota
Sep 12, 2000·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·H Oonishi, Y Kadoya
Dec 14, 2001·The Journal of Arthroplasty·H OonishiH Amino
Dec 9, 2003·Journal of Biomedical Materials Research. Part a·Hironobu OonishiShingo Masuda
Jun 8, 2004·Acta Orthopaedica Scandinavica·Kengo YamamotoAtsuhiro Imakiire
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·F J BuchananS Downes
Apr 5, 2005·The Journal of Bone and Joint Surgery. American Volume·Steven M KurtzAvram A Edidin
May 21, 2005·The Journal of Arthroplasty·Christi J SychterzCharles A Engh
Oct 19, 2005·The Journal of Arthroplasty·Steven M KurtzRichard Rothman
Feb 6, 2007·Journal of Biomaterials Science. Polymer Edition·Masayuki KyomotoHironobu Oonishi

❮ Previous
Next ❯

Citations

Jun 7, 2015·Expert Review of Medical Devices·Carmen ZietzRobert Sonntag

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association
Katsutoshi HaraTakehiko Torisu
© 2021 Meta ULC. All rights reserved