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Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I

The Journal of Biological Chemistry

Apr 7, 2000

Ute PanzenböckRoland Stocker

Abstract

The initial stage of oxidation of high density lipoproteins (HDL) is accompanied by the lipid hydroperoxide-dependent, selective oxidation of two of the three Met residues of apolipoprotein A-I (apoA-I) to Met sulfoxides (Met(O)). Formation of such selectively oxidized apoA-I (i.e. apoA...read more

Mentioned in this Paper

APOA1 gene
LCAT gene
Cholesterol Measurement Test
Phospholipid Measurement
Specimen Type - Macrophages
LDL-1
Phosphatidylcholine-Sterol O-Acyltransferase
Vesicle
Lipid Peroxides
Lipids
19
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Oxidation of methionine residues to methionine sulfoxides does not decrease potential antiatherogenic properties of apolipoprotein A-I

The Journal of Biological Chemistry

Apr 7, 2000

Ute PanzenböckRoland Stocker

PMID: 10751387

DOI: 10.1074/jbc.m000458200

Abstract

The initial stage of oxidation of high density lipoproteins (HDL) is accompanied by the lipid hydroperoxide-dependent, selective oxidation of two of the three Met residues of apolipoprotein A-I (apoA-I) to Met sulfoxides (Met(O)). Formation of such selectively oxidized apoA-I (i.e. apoA...read more

Mentioned in this Paper

APOA1 gene
LCAT gene
Cholesterol Measurement Test
Phospholipid Measurement
Specimen Type - Macrophages
LDL-1
Phosphatidylcholine-Sterol O-Acyltransferase
Vesicle
Lipid Peroxides
Lipids
19

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