Oxidative Stress and Dietary Fat Type in Relation to Periodontal Disease

Antioxidants
Alfonso Varela-LópezPedro Bullón

Abstract

Oxidative stress is one of the main factors studied to explain the pathophysiological mechanisms of inflammatory conditions, such as periodontitis. In this respect, nutrition may be of great importance. Actually, research on nutrients' effects on periodontal diseases has expanded to include those influencing the redox status, which correlates to the inflammatory process. Dietary fat or lipids are often blamed as the major source of excess energy. Consequently, when caloric intake exceeds energy expenditure, the resultant substrate-induced increase in citric acid cycle activity generates an excess of reactive oxygen species (ROS). In addition, dietary fatty acid intake influences in relative fatty acid composition of biological membranes determining its susceptibility to oxidative alterations. From this standpoint, here, we reviewed studies analyzing the dietary fat role in periodontal disease. Research data suggest that periodontal health could be achieved by main dietary strategies which include substitution of saturated fats with monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), particularly n-3 PUFA. Maybe in the future, we should analyze the diet and provide some advice to periodontitis patients to ...Continue Reading

References

May 1, 1992·Comparative Biochemistry and Physiology. Comparative Physiology·M D GironM D Suarez
Nov 27, 1991·Biochemical and Biophysical Research Communications·J R HuertasG Lenaz
Jan 1, 1991·Free Radical Biology & Medicine·H EsterbauerH Zollner
May 1, 1995·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·M SalamiF Visioli
Mar 13, 1993·BMJ : British Medical Journal·F DeStefanoC M Russell
May 1, 1997·Journal of Clinical Periodontology·I L Chapple
Jan 23, 1998·Lipids·K J Ayre, A J Hulbert
Jan 27, 1998·Journal of Clinical Periodontology·P CampanD Duran
Sep 2, 1998·Annals of Periodontology·R I GarciaP S Vokonas
Oct 17, 1998·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·K Simkiss
Jun 12, 1999·European Journal of Clinical Nutrition·R UauyA Valenzuela
Aug 18, 1999·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·J L QuilesJ Mataix
Aug 2, 2000·The American Journal of Clinical Nutrition·H L Newmark
Aug 5, 2000·Free Radical Biology & Medicine·Y M Janssen-HeiningerP A Baeuerle
Jan 29, 2002·Journal of Periodontology·M BattinoP Bullon
Feb 21, 2002·Journal of Agricultural and Food Chemistry·Rianne LeenenFrans H M M van de Put
Mar 13, 2002·Annals of Periodontology·A M Iacopino
Mar 13, 2002·Annals of Periodontology·W A Soskolne, A Klinger
Apr 27, 2002·Annals of the New York Academy of Sciences·Reinald PamplonaManuel Portero-Otín
Jun 19, 2002·Free Radical Research·Siro PassiGian Paolo Littarru
Sep 10, 2002·Trends in Biochemical Sciences·James G WallisJohn Browse
Feb 20, 2003·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Elliot D RosensteinGregory Kazandjian
Mar 4, 2003·The Journal of Nutrition·Lenore Arab
May 29, 2004·European Journal of Nutrition·Jaume MarrugatUNKNOWN SOLOS Investigators
Jun 12, 2004·Journal of Clinical Periodontology·G R BrockI L C Chapple
Feb 22, 2005·Journal of Lipid Research·Eoin FahyEdward A Dennis

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Citations

Jul 28, 2016·International Journal of Molecular Sciences·Alfonso Varela-LópezJosé L Quiles
Sep 13, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alfonso Varela-LópezJosé L Quiles
Oct 18, 2016·Scientific Reports·Chung-Jung ChiuAllen Taylor
Jul 18, 2017·International Journal of Molecular Sciences·Subbroto Kumar SahaSsang-Goo Cho
May 23, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alfonso Varela-LópezJosé L Quiles
Aug 2, 2017·Asian Pacific Journal of Tropical Medicine·Sandra Mara Pimentel DuavyNilda Vargas Barbosa

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