Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease

Nutrients
Julia Lorenzon Dos SantosAline Marcadenti

Abstract

Atherosclerosis is related to fat accumulation in the arterial walls and vascular stiffening, and results in acute coronary syndrome which is commonly associated with acute myocardial infarction. Oxidative stress participates in the pathogenesis of atherosclerosis. Thus, the inclusion of food sources of dietary antioxidants, such as different kinds of nuts, may improve biomarkers related to oxidative stress, contributing to a possible reduction in atherosclerosis progression. This article has briefly highlighted the interaction between oxidative stress, atherosclerosis, and cardiovascular disease, in addition to the effect of the consumption of different nuts and related dietary antioxidants-like polyphenols and vitamin E-on biomarkers of oxidative stress in primary and secondary cardiovascular prevention. Studies in vitro suggest that nuts may exert antioxidant effects by DNA repair mechanisms, lipid peroxidation prevention, modulation of the signaling pathways, and inhibition of the MAPK pathways through the suppression of NF-κB and activation of the Nrf2 pathways. Studies conducted in animal models showed the ability of dietary nuts in improving biomarkers of oxidative stress, such as oxLDL and GPx. However, clinical trials ...Continue Reading

References

Sep 21, 2000·The American Journal of Medicine·D J Lefer, D N Granger
Nov 6, 2001·The Journal of Nutrition·K J AndersonF M Steinberg
Jun 12, 2003·Journal of Agricultural and Food Chemistry·Giacomo DugoMaria Alfa
Jun 23, 2005·Journal of Agricultural and Food Chemistry·Joana S AmaralBeatriz P P Oliveira
Jun 22, 2006·Journal of Agricultural and Food Chemistry·Mahesh Venkatachalam, Shridhar K Sathe
Nov 28, 2006·International Journal of Food Sciences and Nutrition·E RyanN M O'Brien
May 8, 2008·Nature Clinical Practice. Cardiovascular Medicine·Ulrich Förstermann
Nov 6, 2009·Journal of Agricultural and Food Chemistry·Eui-Cheol ShinRonald R Eitenmiller
Jan 13, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Patricia López-UriarteJordi Salas-Salvadó
Mar 23, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Andor W J M GlaudemansAlberto Signore
Mar 23, 2010·Pflügers Archiv : European journal of physiology·Ulrich Förstermann
Nov 4, 2010·European Journal of Clinical Nutrition·J Pérez-JiménezA Scalbert
Sep 6, 2011·The American Journal of Cardiology·Maria Cristina D ThomazellaFrancisco R M Laurindo
Dec 17, 2011·The British Journal of Nutrition·Stefanie LuxMichael Glei
Mar 15, 2013·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·R Zamora-RosUNKNOWN PREDIMED Study Investigators
Apr 2, 2013·Heart, Lung & Circulation·Kenichi SakakuraRenu Virmani
Jun 19, 2013·Nature Cell Biology·Juan Carlos AcostaJesús Gil
Nov 22, 2013·The New England Journal of Medicine·Ying BaoCharles S Fuchs
Feb 8, 2014·Biological Trace Element Research·Milena Barcza Stockler-PintoOlaf Malm
May 13, 2014·European Journal of Nutrition·Lucia LaubertováIngrid Zitňanová
Aug 26, 2014·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·A P N BentoM M V Naves
Sep 23, 2014·Atherosclerosis·Huige LiUlrich Förstermann
Feb 24, 2015·F1000prime Reports·John A Ambrose, Manmeet Singh
May 30, 2015·Nutrition Journal·Grazielle V B HugueninGlorimar Rosa
Jul 4, 2015·Arteriosclerosis, Thrombosis, and Vascular Biology·Sarah E GardnerMurray C H Clarke
Jul 8, 2015·The British Journal of Nutrition·Cesarettin Alasalvar, Bradley W Bolling
Dec 30, 2015·Critical Reviews in Food Science and Nutrition·Claudia Sánchez-GonzálezMaria Izquierdo-Pulido
Apr 25, 2016·International Journal of Cardiology·Giuseppe LippiGianfranco Cervellin
Oct 25, 2016·The Journal of Nutritional Biochemistry·Youngshim ChoiByoung-Joon Song
Sep 11, 2017·Food Research International·Bárbara R CardosoSilvia M F Cozzolino

❮ Previous
Next ❯

Citations

Sep 10, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariusz BanachWojciech Kujawski
Mar 9, 2021·Journal of Food Science and Technology·Elif Yildiz, Duygu Gocmen
May 1, 2021·International Journal of Molecular Sciences·Diana Jhoseline Medina-LeyteLeonor Jacobo-Albavera
Jun 3, 2021·International Journal of Molecular Sciences·Teresa GervasiGiuseppina Mandalari
Aug 5, 2021·Trends in Food Science & Technology·Gitishree DasJayanta Kumar Patra
Oct 7, 2021·Diabetes/metabolism Research and Reviews·João Leonardo Silveira RossiLance Alan Sloan

❮ Previous
Next ❯

Methods Mentioned

BETA
MDA

Software Mentioned

EVOO
MeDiet
MN

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

Anales del sistema sanitario de Navarra
K B F BarbosaJ A Martínez Hernández
Nutrition Reviews
Patricia López-UriarteJordi Salas-Salvadó
The American Journal of Cardiology
Stephen D Nash, Matthew Westpfal
The Manchester Medical Gazette
P Bohan
© 2021 Meta ULC. All rights reserved