Oxidative stress imaging in live animals with techniques based on electron paramagnetic resonance.

Radiation Research
Martyna ElasHoward J Halpern

Abstract

Oxidative stress has been the object of considerable biological and biochemical investigation. Quantification has been difficult although the quantitative level of products of biological oxidations in tissues and tissue products has emerged as a widely used technique. The relationship between these products and the amount of oxidative stress is less clear. Imaging oxidative stress with electron paramagnetic resonance related magnetic resonance imaging, while not addressing the specific issue of quantification of initiating events, focuses on the anatomic specific location of the oxidative stress. Moreover, the relative quantification of oxidative stress of one location against another is possible, sharpening our understanding of oxidative stress. This promises to improve our understanding of oxidative stress and its deleterious consequences and enhance our understanding of the effectiveness of interventions to modulate oxidative stress and its consequences.

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Citations

Sep 24, 2013·Journal of Magnetic Resonance·Joshua R BillerGareth R Eaton
Oct 15, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David H JohnsonJay L Zweier
Apr 23, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Håkan GustafssonHelene Zachrisson
May 4, 2016·Antioxidants & Redox Signaling·Giuseppe MaulucciMarco De Spirito
Sep 15, 2012·Journal of Magnetic Resonance·Sandra S Eaton, Gareth R Eaton
Jul 11, 2020·NMR in Biomedicine·Soham A ShahFrederick H Epstein
Mar 12, 2021·International Journal of Radiation Biology·Rebecca A D'AlonzoMartin A Ebert

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Methods Mentioned

BETA
imaging techniques
imaging technique
nuclear magnetic resonance

Software Mentioned

OMRI

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