Oxidative stress in alzheimer's disease: A review on emergent natural polyphenolic therapeutics

Complementary Therapies in Medicine
Luke CassidyDaniel A Broszczak

Abstract

The aim of this research was to review the literature on Alzheimer's disease (AD) with a focus on polyphenolics as antioxidant therapeutics. This review included a search of the literature up to and including September 2019 in PubMed and MEDLINE databases using search terms that included: Alzheimer's Disease, Aβ peptide, tau, oxidative stress, redox, oxidation, therapeutic, antioxidant, natural therapy, polyphenol. Any review articles, case studies, research reports and articles in English were identified and subsequently interrogated. Citations within relevant articles were also examined for consideration in this review. Alzheimer's disease is a neurodegenerative disorder that is clinically characterised by the progressive deterioration of cognitive functions and drastic changes in behaviour and personality. Due to the significant presence of oxidative damage associated with abnormal Aβ accumulation and neurofibrillary tangle deposition in AD patients' brains, antioxidant drug therapy has been investigated as potential AD treatment. In particular, naturally occurring compounds, such as plant polyphenols, have been suggested to have potential neuroprotective effects against AD due to their diverse array of physiological actions...Continue Reading

Citations

Apr 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Razvan Stefan BoiangiuOana Cioanca
Jun 11, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Cristina VassalleLaura Sabatino
Jul 28, 2020·Journal of Food Biochemistry·Azzurra StefanucciAdriano Mollica
Oct 10, 2020·Phytotherapy Research : PTR·Giuseppe DerosaFrancesco Di Pierro
Jan 20, 2021·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Lingxiao ZhangDaishun Ling
Jan 29, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Antonis VerverisMichael Plioukas
Mar 7, 2021·Antioxidants·Anna Maria Fratta Pasini, Luciano Cominacini
Mar 9, 2021·Frontiers in Aging Neuroscience·Afzal MisraniLi Yang
Apr 7, 2021·The Journal of Pharmacy and Pharmacology·Joel B JohnsonMani Naiker
May 6, 2021·Acta Neurobiologiae Experimentalis·Mehmet Arif IcerMakbule Gezmen-Karadag
May 25, 2021·Journal of Alzheimer's Disease : JAD·Suélen Santos AlvesNorberto Garcia-Cairasco
Jun 20, 2021·Advanced Drug Delivery Reviews·Lingxiao ZhangFangyuan Li
Jul 3, 2021·International Journal of Molecular Sciences·Ivana Sirangelo, Clara Iannuzzi
Jul 31, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Mukta AgrawalAmit Alexander
Aug 14, 2021·Cell Stress & Chaperones·Elham RazaniDavood Bashash
Aug 18, 2021·Journal of Chemical Neuroanatomy·Vaibhav OliPravir Kumar
Aug 28, 2021·Life Sciences·Dapinder KaurSimona Bungau

❮ Previous
Next ❯

Related Concepts

Related Feeds

Alzheimer's Disease: Amyloid Beta

Alzheimer's disease is a neurodegenerative disease associated with the accumulation of amyloid plaques in the brain; these plaques are comprised of amyloid beta deposits. Here is the latest research in this field.

Alzheimer's Disease: Tau & TDP-43

Alzheimer's disease is a neurodegenerative disease. This feed focuses on the underlying role of tau proteins and TAR DNA-binding protein 43, as well as other genetic factors, in Alzheimer's disease.

Related Papers

Journal of Clinical and Diagnostic Research : JCDR
Adnan Bashir BhattiSiddique Akbar Satti
Neuroscience Bulletin
Zhichun Chen, Chunjiu Zhong
Sheng li xue bao : [Acta physiologica Sinica]
Xiao-Jie LiuJin-Shun Qi
© 2021 Meta ULC. All rights reserved