Oxidative stress level in fresh ejaculate is not related to semen parameters or to pregnancy rates in cycles with donor oocytes

Journal of Assisted Reproduction and Genetics
Aïda PujolR Vassena

Abstract

The purpose of the present study is to study the relationship between oxidative stress (OS) in semen, semen characteristics, and reproductive outcomes in oocyte donation intracytoplasmic sperm injection (ICSI) cycles. OS was measured in 132 semen samples. OS levels were as follows: very high (1.5 %), high (43.2 %), low (30.3 %), and very low (25.0 %). Overall seminal parameters were as follows: volume (ml) = 4.2 (SD 2.1), concentration (millions/ml) = 61.6 (SD 59.8), motility (a+b%) = 47.4 (SD 18.0), and normal spermatozoa (%) = 8.2 (SD 5.1). Of the 101 cycles that reached embryo transfer, 55.4 % evolved in biochemical, 46.5 % in clinical, and 43.6 % in ongoing pregnancy. OS level does not relate to seminal parameters, fertilization rate, or pregnancy outcomes. OS testing by nitro blue tetrazolium (NBT) in fresh ejaculate might not be useful for all patients. Reproductive results with young oocytes and ICSI do not seem to be affected by OS-level semen.

References

Jan 1, 1995·Journal of Assisted Reproduction and Genetics·S OehningerG Hodgen
Jul 1, 1996·Journal of Assisted Reproduction and Genetics·C H YeungE Nieschlag
May 30, 2003·Human Reproduction·Steffen LoftJens Peter Bonde
Mar 16, 2007·Reproductive Biomedicine Online·B OzmenS Al-Hasani
Oct 9, 2007·Biochimica Et Biophysica Acta·Eve de Lamirande, Cristián O'Flaherty
Nov 6, 2007·Proceedings of the National Academy of Sciences of the United States of America·F MarchettiA J Wyrobek
Jan 29, 2008·Zygote : the Biology of Gametes and Early Embryos·C BadouardA Favier
Feb 19, 2008·Human Reproduction Update·Kelton Tremellen
Jun 12, 2008·Systems Biology in Reproductive Medicine·Frédéric LeducGuylain Boissonneault
Dec 17, 2008·International Journal of Andrology·Ozlem TuncKelton Tremellen
May 27, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Monis Bilal ShamsiRima Dada
Jun 16, 2009·Nature·Saher Sue HammoudBradley R Cairns
Aug 4, 2009·Molecular Human Reproduction·R J Aitken, G N De Iuliis
Jan 19, 2010·Fertility and Sterility·Denny Sakkas, Juan G Alvarez
Oct 25, 2011·Reproductive Biomedicine Online·Marga EsbertGloria Calderón
Dec 4, 2012·International Journal of Molecular Sciences·Clara González-MarínRosa Roy
Aug 21, 2013·Free Radical Biology & Medicine·Anais NoblancAyhan Kocer
Mar 13, 2014·Iranian Red Crescent Medical Journal·Abasalt Hosseinzadeh ColagarSeyed Gholam Ali Jorsaraei
Jun 3, 2014·Reproductive Biology and Endocrinology : RB&E·Ashok AgarwalRakesh Sharma
Nov 12, 2014·Reproduction : the Official Journal of the Society for the Study of Fertility·Tania Morielli, Cristian O'Flaherty
Dec 3, 2014·Fertility and Sterility·Edmund Y KoAshok Agarwal

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Citations

Dec 11, 2019·Antioxidants·Ana Izabel Silva Balbin VillaverdeMark A Baker

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