Oxidative stress-modulating drugs have preferential anticancer effects - involving the regulation of apoptosis, DNA damage, endoplasmic reticulum stress, autophagy, metabolism, and migration

Seminars in Cancer Biology
Jen-Yang TangHsueh-Wei Chang

Abstract

To achieve preferential effects against cancer cells but less damage to normal cells is one of the main challenges of cancer research. In this review, we explore the roles and relationships of oxidative stress-mediated apoptosis, DNA damage, ER stress, autophagy, metabolism, and migration of ROS-modulating anticancer drugs. Understanding preferential anticancer effects in more detail will improve chemotherapeutic approaches that are based on ROS-modulating drugs in cancer treatments.

Citations

Oct 20, 2018·Metallomics : Integrated Biometal Science·Clara BalsanoSilvia Sideri
Aug 23, 2019·World Journal of Gastrointestinal Oncology·Si-Si LiRong Wan
Nov 11, 2019·Journal of Experimental & Clinical Cancer Research : CR·Lihua WangTongke Chen
Jan 15, 2019·Journal of Cellular Biochemistry·Qi-Quan WuWei-Zhi Zhu
Apr 20, 2019·Oxidative Medicine and Cellular Longevity·Huizhen Wang, Xin Zhang
Dec 16, 2019·RSC Medicinal Chemistry·Martin DomXaveer Van Ostade
Dec 9, 2020·Nutrients·Kaja Michalczyk, Aneta Cymbaluk-Płoska
Jun 2, 2020·International Journal of Biological Macromolecules·Jun WangChuanlong Guo
Mar 23, 2021·Oxidative Medicine and Cellular Longevity·Hui-Ru WangHsueh-Wei Chang
May 15, 2021·Journal of the Science of Food and Agriculture·Cong JiaJinian Huang
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sheng-Chieh WangHsueh-Wei Chang

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