Oximetry and neonatal examination for the detection of critical congenital heart disease: a systematic review and meta-analysis

F1000Research
Hernán Camilo Aranguren BelloRodolfo José Dennis Verano

Abstract

Background: Undiagnosed congenital heart disease in the prenatal stage can occur in approximately 5 to 15 out of 1000 live births; more than a quarter of these will have critical congenital heart disease (CCHD). Late postnatal diagnosis is associated with a worse prognosis during childhood, and there is evidence that a standardized measurement of oxygen saturation in the newborn by cutaneous oximetry is an optimal method for the detection of CCHD. We conducted a systematic review of the literature and meta-analysis comparing the operational characteristics of oximetry and physical examination for the detection of CCHD. Methods: A systematic review of the literature was conducted on the following databases including published studies between 2002 and 2017, with no language restrictions: Pubmed, Science Direct, Ovid, Scopus and EBSCO, with the following keywords: oximetry screening, critical congenital heart disease, newborn OR oximetry screening heart defects, congenital, specificity, sensitivity, physical examination. Results: A total of 419 articles were found, from which 69 were selected based on their titles and abstracts. After quality assessment, five articles were chosen for extraction of data according to inclusion crite...Continue Reading

References

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Feb 16, 2011·Circulation·Helen DolkUNKNOWN European Surveillance of Congenital Anomalies (EUROCAT) Working Group
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Apr 29, 2014·Lancet·Qu-ming ZhaoUNKNOWN Neonatal Congenital Heart Disease screening group
Sep 23, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Juliette L OakleySiddhartha Sen
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Sep 25, 2017·Pediatrics·Xiao-Jing HuGuo-Ying Huang
Jan 27, 2018·Academic Radiology·Paul CroninBen A Dwamena

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Citations

Jul 10, 2019·Cost Effectiveness and Resource Allocation : C/E·Dario Londoño TrujilloRodolfo Jose Dennis

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Software Mentioned

STATA
Ovid
EBSCO
Scopus
RevMan

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