Oxygen affinity in the blood of sheep

Respiration Physiology
M Samaja, L Gattinoni


The oxygen affinity in the blood of adult Dorset sheep with HbB was studied by determining several oxygen equilibrium curves under different conditions of pH and PCO2 by a method that allowed strict control of pH, PCO2, and HCO3- concentration over the entire curve. Nomograms and equations were derived that allowed the estimation of the oxygen saturation in a sample of blood in the range 0 to 100%, either from pH, PCO2 and PO2, or from PO2 and known P50. The advantage of this approach is that no assumptions about the shape of the oxygen equilibrium curve need be made (i.e. the Hill parameter, n, is not required to be constant), since the entire curve was measured.


Nov 5, 1976·Pflügers Archiv : European journal of physiology·N TakanoK Matsue
Jul 1, 1975·New Zealand Veterinary Journal·G V Wallace
Jan 1, 1961·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·G MESCHIAD H BARRON


Oct 15, 1979·Experientia·L Gattinoni, M Samaja
Jan 1, 1989·Annals of Biomedical Engineering·M SharanA S Popel
Jan 1, 1989·Journal of Biomedical Engineering·M Sharan, A S Popel
Nov 10, 2018·Intensive Care Medicine Experimental·Judith BellapartJohn F Fraser
Jul 1, 1980·British Journal of Haematology·N MaedaT Shiga

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