PMID: 9692118Aug 6, 1998

Oxygen, arterial blood gases and ventilation are unchanged during dialysis in patients receiving pressure support ventilation

Respiratory Medicine
C C HuangT C Tsao

Abstract

This study was undertaken to observe whether dialysis-induced alveolar hypoventilation and arterial hypoxaemia occur during bicarbonate haemodialysis in patients receiving partial mechanical support with pressure support ventilation. Nineteen patients admitted to the medical intensive care unit requiring mechanical ventilation and haemodialysis were enrolled. Arterial blood gas, white blood cell (WBC) count, minute ventilation, respiratory rate, breathing pattern and blood pressure were measured according to the following time schedule: pre-dialysis (time 0), and at 15, 30, 60, 120, 180, 240 min thereafter. Results showed that, with the use of cuprammonium dialyser, the WBC count dropped immediately and reached the nadir 15 min after haemodialysis. Thereafter, it recovered and overshot the pre-dialysis values until the end of dialysis. The bicarbonate dialysate indeed resulted in rapid and significant metabolic alkalosis. However, no decrease of PaO2 occurred throughout haemodialysis. The tidal volume, minute ventilation and breathing pattern remained stable during haemodialysis. We conclude that neither dialysis-induced alveolar hypoventilation nor arterial hypoxaemia developed during bicarbonate dialysis in patients mechanica...Continue Reading

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Citations

Nov 12, 2013·Revista Brasileira de terapia intensiva·Fernanda Maia LopesDimitri Gusmao-Flores
Oct 6, 2018·Hemodialysis International·Cibele Puato de AlmeidaAndré Luís Balbi
Jan 23, 2014·Journal of Homosexuality·Lorraine K McDonaghTodd G Morrison
Jun 28, 2018·Clinical and Experimental Nephrology·Cibele Puato AlmeidaDaniela Ponce

Related Concepts

Anoxemia
Blood Gas Analysis
Carbon Dioxide
Hemodialysis
Hemodynamics
Kidney Failure, Chronic
Differential White Blood Cell Count Procedure
Dioxygen
Pulmonary Alveolar Structure
Respiration

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