PMID: 37193Jan 1, 1979

Oxygen binding of fetal and adult bovine hemoglobin in the presence of organic phosphates and uric acid riboside

R C SmithD R Harkness


The P50 values of "stripped" fetal and adult bovine hemoglobin were 18.4 and 28.9 respectively. Neither the oxygen-hemoglobin dissociation curve nor the Hill coefficient, n, of fetal or adult bovine hemoglobin was affected by uric acid riboside (UAR), 2,3-diphosphoglyceric acid (2,3-DPG), adenosine triphosphate (ATP), or inositol pentaphosphate (IPP). Combinations of UAR and ATP with adult bovine hemoglobin or 2,3-DPG and ATP with fetal hemoglobin also had no effect. It was concluded that neither adult nor fetal bovine red cells contained an identifiable compound which affects the binding of oxygen to hemoglobin.


Dec 1, 1975·Journal of Animal Science·R C Smith, C M Stricker
May 23, 1976·Biochemical and Biophysical Research Communications·R C Smith, C M Stricker
Aug 1, 1975·Science·R E Isaacks, D R Harkness
Jul 1, 1973·Comparative Biochemistry and Physiology. A, Comparative Physiology·J Zinkl, J J Kaneko
Nov 29, 1974·Annals of the New York Academy of Sciences·H F BunnA F Scott
Jun 1, 1970·The Journal of Clinical Investigation·H F Bunn, R W Briehl
Jul 1, 1970·The American Journal of Physiology·F C BATTAGLIAG Meschia
Jan 1, 1969·Archives of Biochemistry and Biophysics·I Tyuma, K Shimizu
Aug 1, 1964·Clinica Chimica Acta; International Journal of Clinical Chemistry·C M NECHTMAN, T H HUISMAN


Mar 1, 1981·Pflügers Archiv : European journal of physiology·P M BreepoelM Hazevoet
Jan 1, 1988·Comparative Biochemistry and Physiology. A, Comparative Physiology·P GustinA Frans
Jun 11, 2005·Research in Veterinary Science·Steve C Haskins, Marlis L Rezende
May 15, 1988·Archives of Biochemistry and Biophysics·R E WeberG Braunitzer
Mar 1, 1997·Journal of Applied Physiology·P GustinT Clerbaux
Mar 1, 1981·Pflügers Archiv : European journal of physiology·P M BreepoelM Hazevoet

Related Concepts

Adenosine Triphosphate, Chromium Ammonium Salt
Bos indicus
Diphosphoglyceric Acids
Fetal Hemoglobin
Hemoglobin A
Hydrogen-Ion Concentration
Inositol Phosphates
Organopyrophosphorus Compounds
Oxygen Consumption

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