PMID: 1713490Feb 1, 1991

Oxygen-binding properties of bat hemoglobins

Archives Internationales De Physiologie, De Biochimie Et De Biophysique
F ArévaloP López-Luna


The functional properties of hemolysates from the bats Rhinolophus ferrumequinum, Miniopterus schreibersi and Pipistrellus pipistrellus were studied at 25 degrees C and 37 degrees C over the pH range 7.0-7.4. The concentrations of 2,3-DPG and their effect on hemoglobin O2 affinity were also studied under the same conditions. At pH 7.4 and 37 degrees C hemoglobin O2 affinity was higher than in similarly-sized non-flying, normothermic mammals. The Bohr effect values in the three bat species were slightly lower than those reported for small non-flying mammals. The temperature sensitivities of the oxygenation reactions in bat hemoglobins were low, which may be a mechanism for avoiding the effects of abrupt body temperature changes on oxygen loading and unloading by hemoglobin. The levels of 2, 3-DPG high in red blood cells of active bats decrease when the bats are hibernating. Thus changes in hemoglobin O2 affinity are more probably due to changes in 2,3-DPG concentrations than to alterations of body temperature.


Aug 1, 1975·The American Journal of Physiology·S Lahiri
Feb 1, 1975·Proceedings of the Society for Experimental Biology and Medicine·G E Tempel, X J Musacchia
Jan 1, 1986·Comparative Biochemistry and Physiology. A, Comparative Physiology·G Pérez-SuárezP López-Luna
Jan 1, 1987·Comparative Biochemistry and Physiology. A, Comparative Physiology·F ArévaloP López-Luna
Jul 1, 1974·Comparative Biochemistry and Physiology. A, Comparative Physiology·D R HarknessP Goldman
Feb 1, 1971·Comparative Biochemistry and Physiology. A, Comparative Physiology·R F Burlington, B K Whitten
Nov 29, 1974·Annals of the New York Academy of Sciences·H F BunnA F Scott
Jun 1, 1973·Journal of Applied Physiology·P W RandW H Austin
Jan 1, 1984·Comparative Biochemistry and Physiology. A, Comparative Physiology·J E Bassett, C A Wiederhielm
May 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·J QvistW M Zapol
Jan 1, 1981·Methods in Enzymology·A Riggs
Sep 1, 1981·Respiration Physiology·K D JürgensR Bartels
Jan 15, 1980·Journal of Molecular Biology·M F Perutz, K Imai
Nov 1, 1958·The American Journal of Physiology·K SCHMIDT-NEILSEN, J L LARIMER
Oct 1, 1958·Archives of Biochemistry and Biophysics·A ROSSI-FANELLI, E ANTONINI


Related Concepts

Diphosphoglyceric Acids
Hydrogen-Ion Concentration
2,3-Diphosphoglycerate, (D)-Isomer

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Systemic Juvenile Idiopathic Arthritis

Systemic juvenile idiopathic arthritis is a rare rheumatic disease that affects children. Symptoms include joint pain, but also fevers and skin rashes. Here is the latest on this disease.

Chromatin Regulation and Circadian Clocks

The circadian clock plays an important role in regulating transcriptional dynamics through changes in chromatin folding and remodelling. Discover the latest research on Chromatin Regulation and Circadian Clocks here.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

Pontocerebellar Hypoplasia

Pontocerebellar hypoplasias are a group of neurodegenerative autosomal recessive disorders with prenatal onset, atrophy or hypoplasia of the cerebellum, hypoplasia of the ventral pons, microcephaly, variable neocortical atrophy and severe mental and motor impairments. Here is the latest research on pontocerebellar hypoplasia.

Cell Atlas Along the Gut-Brain Axis

Profiling cells along the gut-brain axis at the single cell level will provide unique information for each cell type, a three-dimensional map of how cell types work together to form tissues, and insights into how changes in the map underlie health and disease of the GI system and its crosstalk with the brain. Disocver the latest research on single cell analysis of the gut-brain axis here.

Chronic Traumatic Encephalopathy

Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease that occurs in individuals that suffer repetitive brain trauma. Discover the latest research on traumatic encephalopathy here.