PMID: 2492815Jan 1, 1989Paper

Oxygen consumption and carbon dioxide elimination in infants and children during anaesthesia and surgery

British Journal of Anaesthesia
S G Lindahl

Abstract

Oxygen consumption (VO2, ml min-1) and carbon dioxide elimination (VCO2, ml min-1), minute ventilation (VE), tidal volume (VT), rate of ventilation (f) and end-tidal carbon dioxide concentration (E'CO2%) were measured in 38 infants and children (body weights 3.6-25 kg). Four children (body weight less than 5 kg) had congenital heart malformations and were studied during controlled mechanical ventilation, whereas the remainder (n = 34) who were healthy, breathed spontaneously. Anaesthesia was maintained with oxygen in air (FIO2 0.45) and halothane through a non-rebreathing circuit. Minute ventilation was measured by pneumotachography, E'CO2 with an in-line infra-red carbon dioxide meter and gas concentrations with a mass spectrometer. There were no differences in VO2 and VCO2 between children with and without heart disease. VO2 was related to body weight by the equation: VO2 = 5.0 x kg + 19.8 (r = 0.94) and VCO2 to body weight by the equation: VCO2 = 4.8 x kg + 6.4 (r = 0.94). There were no differences between VO2 or VCO2 before and after the start of surgery. In 11 of 21 patients weighing less than 10 kg, a reduced VCO2 was noted, giving respiratory quotients of less than 0.7. It is speculated that this age-dependent variation ...Continue Reading

Citations

Sep 1, 1994·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R PatelW A McGill
Mar 1, 1995·Journal of Clinical Anesthesia·F S XueG An
Nov 1, 1996·Journal of Clinical Anesthesia·F S XueG An
May 9, 2009·Cardiology in the Young·Antonio A Lopes, Patrick W O'Leary
Jan 5, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·V Ben Sivarajan, Desmond Bohn
Jul 31, 2009·Annals of Thoracic Medicine·Antonio Augusto LopesAna Maria Thomaz
Mar 16, 2016·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Zaher FanariAndrew J Doorey
Apr 11, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Jia Li
Feb 6, 1999·Journal of Perianesthesia Nursing : Official Journal of the American Society of PeriAnesthesia Nurses·R A Marley
Nov 7, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Santosh B ShindeAnil G Tendolkar
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Jul 29, 2006·British Journal of Anaesthesia·J G Hardman, J S Wills
Mar 1, 1995·Anesthesia and Analgesia·A KurzF Lackner
Aug 28, 2020·Physiological Reports·Per M GustafssonPaul D Robinson
Jun 9, 2009·Anaesthesia and Intensive Care·C R Stuart-AndrewsB Lithgow
Sep 13, 2014·Journal of Applied Physiology·Mahesh DharmakumaraBruce R Thompson
May 20, 2021·Paediatric Anaesthesia·Susan HumphreysBritta S von Ungern-Sternberg

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