Jan 27, 2015

Oxygen-evolving complex of Photosystem II: an analysis of second-shell residues and hydrogen-bonding networks

Current Opinion in Chemical Biology
Leslie VogtGary W Brudvig

Abstract

The oxygen-evolving complex (OEC) is a Mn4O5Ca cluster embedded in the Photosystem II (PSII) protein complex. As the site of water oxidation, the OEC is connected to the lumen by channels that conduct water, oxygen, and/or protons during the catalytic cycle. The hydrogen-bond networks found in these channels also serve to stabilize the oxidized intermediates, known as the S states. We review recent developments in characterizing these networks via protein mutations, molecular inhibitors, and computational modeling. On the basis of these results, we highlight regions of the PSII protein in which changes have indirect effects on the S1, S2, and S3 oxidation states of the OEC while still allowing photosynthetic activity.

  • References46
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Citations

Mentioned in this Paper

Entire Lumen of Body System
Oxidation
Protein Complex Location
Structure of Lumen of Body System
Photosystem II
Protein complex

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