Oxygenated cembranoids from a Formosan soft coral Sinularia gibberosa

Journal of Natural Products
Atallah Fouad AhmedJyh-Horng Sheu

Abstract

Chemical investigation of a Formosan soft coral, Sinularia gibberosa, has led to the isolation of eight oxygenated cembranoids, 1- 8, including seven new compounds, gibberosenes A-G ( 2- 8). None of these compounds were found to be cytotoxic toward a limited panel of cancer cell lines. Compound 1 significantly inhibited the accumulation of the pro-inflammatory COX-2 protein of the LPS-stimulated RAW264.7 macrophage cells.

References

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Nov 26, 2002·Journal of Natural Products·Chang-Yih DuhChang-Feng Dai
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Dec 29, 2004·Journal of Natural Products·Atallah F AhmedJyh-Horng Sheu
Jun 1, 2005·Journal of Natural Products·Guoqiang LiWenhan Lin
Aug 12, 2005·Organic Letters·Yen-Ju TsengJyh-Horng Sheu
Aug 30, 2005·Journal of Natural Products·Atallah F AhmedJyh-Horng Sheu
Aug 29, 2006·Journal of Natural Products·Jui-Hsin SuJyh-Horng Sheu
Sep 23, 2006·Journal of Natural Products·Atallah F AhmedJyh-Horng Sheu
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Citations

Sep 13, 2011·Archives of Pharmacal Research·Yi LuJui-Hsin Su
May 31, 2012·Archives of Pharmacal Research·Jui-Hsin SuJyh-Horng Sheu
Apr 23, 2010·Chemical & Pharmaceutical Bulletin·Yi LuJyh-Horng Sheu
Nov 3, 2012·Marine Drugs·Bin YangYonghong Liu
Nov 11, 2011·Marine Drugs·Chih-Hua ChaoJyh-Horng Sheu
Mar 1, 2012·Marine Drugs·Nai-Lun Lee, Jui-Hsin Su
Nov 6, 2015·Mediators of Inflammation·Yisett GonzálezPatricia L Fernandez
Mar 19, 2013·Biotechnology Advances·Saradavey Vinothkumar, P S Parameswaran
Jun 18, 2016·Journal of Asian Natural Products Research·Tarik A MohamedMohamed Elamir F Hegazy
Nov 22, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hai ShangZhong-Mei Zou
Jan 25, 2017·Marine Drugs·Atallah F AhmedJyh-Horng Sheu
Dec 3, 2015·Organic & Biomolecular Chemistry·Marie Pascaline RahelivaoHans-Joachim Knölker
Nov 29, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Wei-Hsuan YenPing-Jyun Sung
Aug 21, 2009·Natural Product Reports·James R Hanson
Jan 30, 2010·Natural Product Reports·John W BluntMichèle R Prinsep
Feb 26, 2019·Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry·Wendy Alexander TanodYenny Risjani
Aug 10, 2019·Marine Drugs·Wan-Ru TsengJyh-Horng Sheu
Apr 7, 2009·The Journal of Organic Chemistry·Leiv K SydnesMiriam Hanstein

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