PMID: 9161895May 1, 1997Paper

Oxygenator anatomy and function

Journal of Cardiothoracic and Vascular Anesthesia
J A Wegner

Abstract

The natural lung is the organ responsible for oxygen and carbon dioxide exchange between the blood and the outside environment. This function is accomplished by the large surface area and high permeability of the gas exchange interface, the alveolar-capillary membrane. These same features are fundamental to the design of an artificial lung, or oxygenator. Additional lung-like features essential to the design of an ideal oxygenator include the ability to achieve balanced oxygen and carbon dioxide exchange with minimal blood damage and blood activation. The purpose of this review is to present the past and current developments of the oxygenator designs in terms of the structural and functional features of the natural lung as well as the limitations in the ability to mimic the features of the lung because of the lack of appropriate technology.

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Citations

Oct 6, 2006·Current Opinion in Anaesthesiology·Preston B Rich, Peter Rock
Mar 19, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ayaka HiranoKiyotaka Sakai
Jun 5, 2003·Annals of the New York Academy of Sciences·S R WickramasingheBinbing Han
Apr 17, 2007·Biomaterials·Joel L KaarWilliam J Federspiel
Dec 20, 2015·PloS One·Maren DietrichChristian G Cornelissen
Feb 24, 2018·Artificial Organs·Rik H J HendrixPatrick W Weerwind
Jan 7, 2006·Journal of Applied Physiology·Colin BorlandAlain Vuylsteke
Jun 14, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Alex J ThompsonRonald B Hirschl
Sep 14, 2006·The International Journal of Artificial Organs·V L OrdodiF A Mic
Jan 1, 2013·Biomolecules·Christopher D BooneRobert McKenna
May 7, 2013·The International Journal of Artificial Organs·Niels RochowChristoph Fusch
Jul 3, 2021·Bioengineering·Ahad SyedAdnan Qamar

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