Oxytocin during myomectomy: a randomized study

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Aubert AgostiniBernard Blanc

Abstract

To evaluate the influence of oxytocin on peroperative blood loss during myomectomy. From October 1998 to May 2002, 94 patients requiring surgical myomectomy by laparotomy or by the vaginal approach were enrolled in a randomized double blind study. Patients were randomized to two groups. In the first group (47 patients) oxytocin was administered during myomectomy and in the second group (47 patients) a placebo was used. The main outcome measures were peroperative blood loss and rates of blood transfusion and autotransfusion. Peroperative blood loss was no different between the oxytocin group and the placebo group (508 +/- 558 ml versus 451 +/- 336 ml; P=0.55). Rates of autotransfusion and blood transfusion were also similar in both groups. Administration of oxytocin during myomectomy did not reduce peroperative blood loss in our study. The benefits of using oxytocin to prevent hemorrhage during myomectomy seem to be limited.

References

Jun 1, 2001·Obstetrics and Gynecology·C R OkinS Ramanathan
Jun 29, 2001·Experimental Physiology·R IvellA R Fuchs
Apr 18, 2002·The Journal of the American Association of Gynecologic Laparoscopists·Moises LichtingerGhea Adeboyejo

Citations

Jun 10, 2010·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Thumuluru Kavitha MadhuriSimon Butler-Manuel
Jan 22, 2011·Reproductive Biomedicine Online·Alberto MatteiGianfranco Scarselli
Nov 10, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·T SongS J Seong
Sep 27, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Eugene J KongnyuyCharles Shey Wiysonge
Mar 21, 2007·Journal of Minimally Invasive Gynecology·Chin-Jung WangYung-Kuei Soong
Feb 9, 2016·Journal of Minimally Invasive Gynecology·Lisa Caronia HickmanTommaso Falcone
Jun 5, 2015·Archives of Gynecology and Obstetrics·Christos IavazzoIoannis D Gkegkes
Feb 26, 2014·American Journal of Obstetrics and Gynecology·Moeun SonJason D Wright
Jul 16, 2015·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Mohamed Abdel-HafeezMina Yacoub
Jul 21, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Alessandro ConfortiGiuseppe De Placido
Aug 16, 2014·The Cochrane Database of Systematic Reviews·Eugene J Kongnyuy, Charles Shey Wiysonge
Nov 20, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·S AtashkhoeiA Asiaei
Oct 18, 2018·Archives of Gynecology and Obstetrics·Berna Aslan ÇetinTayfur Çift

Related Concepts

Blood Transfusion
Double-Blind Method
Eryhem
Uterine Fibroids
Syntocinon
Placebos
Uterine Cancer
Blood Loss, Surgical

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