PMID: 3770280Sep 1, 1986Paper

Oxytocin induction of labour: hyponatraemia and neonatal jaundice

European Journal of Obstetrics, Gynecology, and Reproductive Biology
S W D'SouzaB Richards

Abstract

To determine the effects of fluid restriction in induced labour with oxytocin in 5% dextrose solution, maternal venous blood and fetal cord venous blood were examined in 164 mothers in induced labour and 29 mothers with a spontaneous onset of labour. After satisfactory uterine activity was induced either the oxytocin infusion was managed according to routine delivery unit practice (n = 36), or infusion rates were halved (n = 45), or quartered (n = 43), or discontinued (n = 40). Despite fluid restriction during labour the mean sodium concentration in maternal blood or cord blood had fallen to a similar extent in all four induced groups at delivery. Potassium, urea, creatinine, total protein, and albumin in maternal blood or cord blood were affected differently by induced labour as compared with sodium. The fall in sodium concentration in maternal blood was a more consistent reflection of the total volume of fluid received, mean infusion rates and cord blood sodium after infusion rates were quartered or discontinued. The incidence of hyponatraemia was 5% in mothers and 8% in infants. A comparison of hyponatraemic and normonatraemic cord blood showed no significant differences in serum bilirubin levels or red cell counts, but more...Continue Reading

References

Mar 25, 1978·Lancet
Feb 1, 1979·British Journal of Obstetrics and Gynaecology·S W D'SouzaB Richards
May 1, 1979·Archives of Disease in Childhood·S Singhi, M Singh
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Dec 1, 1975·Archives of Disease in Childhood·S W De SouzaR D Milner
May 1, 1972·JAMA : the Journal of the American Medical Association·D R Gupta, N H Cohen
Dec 1, 1970·The Journal of Obstetrics and Gynaecology of the British Commonwealth·P R Pedlow
Oct 1, 1984·British Journal of Obstetrics and Gynaecology·S SinghiJ S Hall
Sep 5, 1981·British Medical Journal·W O Tarnow-MordiF V Flynn
May 1, 1981·British Journal of Obstetrics and Gynaecology·S A SpencerS Benson
Apr 1, 1980·Clinical Endocrinology·L ReesC G Brook
Feb 28, 1963·The New England Journal of Medicine·J G PETTMAN
Jun 1, 1965·The Journal of Pediatrics·L B ALTSTATT

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Citations

Jun 24, 2010·International Journal of Obstetric Anesthesia·Lawrence C Tsen, Mrinalini Balki
Aug 21, 2018·The Cochrane Database of Systematic Reviews·Sidsel BoieJannet Jh Bakker
Nov 1, 2001·The Cochrane Database of Systematic Reviews·G R Howarth, D J Botha
Jul 6, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Roxane VanspranghelsCharles Garabedian

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