P bodies, stress granules, and viral life cycles.

Cell Host & Microbe
Carla J Beckham, Roy Parker

Abstract

Eukaryotic mRNAs are in a dynamic equilibrium between different subcellular locations. Translating mRNAs can be found in polysomes, mRNAs stalled in translation initiation accumulate in stress granules and mRNAs targeted for degradation or translation repression can accumulate in P bodies. Partitioning of mRNAs between polysomes, stress granules, and P bodies affects rates of translation and mRNA degradation. Host proteins within P bodies and stress granules can enhance or limit viral infection, and some viral RNAs and proteins accumulate in P bodies and/or stress granules. Thus, an important interplay among P bodies, stress granules, and viral life cycles is beginning to emerge.

References

May 20, 1998·Genome Research·S Sandmeyer
May 21, 1999·The Journal of Biological Chemistry·N Mamiya, H J Worman
Apr 12, 2000·Proceedings of the National Academy of Sciences of the United States of America·J DíezP Ahlquist
Jun 22, 2000·Yeast·J F Roth
Nov 9, 2000·Proceedings of the National Academy of Sciences of the United States of America·A O NoueiryP Ahlquist
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·S RashkovaM-L Pardue
Jan 30, 2003·RNA·Michelle SteigerRoy Parker
Mar 19, 2003·The Journal of Cell Biology·Helene TourrièreJamal Tazi
Mar 26, 2003·Annual Review of Phytopathology·Amine O Noueiry, Paul Ahlquist
Apr 10, 2003·Trends in Genetics : TIG·Joseph E WedekindHarold C Smith
Jun 18, 2003·Cell·Reuben S HarrisMichael H Malim
Dec 13, 2003·Proceedings of the National Academy of Sciences of the United States of America·David B KushnerPaul Ahlquist
Jan 30, 2004·Nature Structural & Molecular Biology·Roy Parker, Haiwei Song
Sep 17, 2004·Molecular Biology of the Cell·Natalie GilksPaul Anderson
Oct 7, 2004·The Journal of Biological Chemistry·Qin YuNathaniel R Landau
Oct 28, 2004·Cell·Venkat S R K YedavalliKuan-Teh Jeang
Dec 8, 2004·Genetics·Michael AyeSuzanne Sandmeyer
Dec 15, 2004·Critical Reviews in Biochemistry and Molecular Biology·Sylke MeyerElmar Wahle
Apr 20, 2005·Genome Research·Becky IrwinSuzanne Sandmeyer
Jun 3, 2005·Molecular Biology of the Cell·Gerald M McInerneyPeter Liljeström
Jun 7, 2005·Nature Cell Biology·Jidong LiuRoy Parker
Sep 6, 2005·Science·Catherine L JoplingPeter Sarnow
Sep 24, 2005·Cell·Jeff Coller, Roy Parker
Jan 28, 2006·Journal of Virology·Jennifer A SmithLeslie A Schiff
Mar 3, 2006·Genes & Development·Marco Antonio Valencia-SanchezRoy Parker
Mar 8, 2006·The Journal of Cell Biology·Paul Anderson, Nancy Kedersha
Oct 13, 2006·The Journal of General Virology·Christy M HebnerLaimonis A Laimins
Dec 15, 2006·Journal of Virology·Sarah Gallois-MontbrunMichael H Malim
Dec 22, 2006·Nature Reviews. Molecular Cell Biology·Ana EulalioElisa Izaurralde

❮ Previous
Next ❯

Citations

Jul 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·Nicoletta SchellerJuana Díez
Jan 23, 2009·Molecular Biology of the Cell·Jason E Duex, Alexander Sorkin
Sep 29, 2011·Nucleic Acids Research·Manuella BouttierCharles-Henri Lecellier
Oct 21, 2009·Antimicrobial Agents and Chemotherapy·Boris NowotnyMarc Kirschner
Jun 24, 2011·Journal of Virology·Katri EskelinKristiina Mäkinen
May 25, 2012·Journal of Virology·Renée L FinnenBruce W Banfield
Jul 30, 2010·Journal of Virology·Ryan BurdickVinay K Pathak
Aug 24, 2012·Journal of Virology·Prabhjeet K PhaloraMichael H Malim
Jun 24, 2011·Journal of Virology·James P WhiteRichard E Lloyd
Jun 21, 2013·Journal of Virology·Yan Zheng, Margaret Kielian
Aug 10, 2012·Journal of Virology·Nicholas L BairdJack H Nunberg
Nov 26, 2010·Journal of Virology·Anthony Khong, Eric Jan
Dec 15, 2010·Journal of Virology·M Simpson-HolleyJ H Connor
May 6, 2011·Journal of Virology·Yasuo AriumiNobuyuki Kato
Apr 29, 2011·Journal of Virology·Chunye LuB Matija Peterlin
Mar 29, 2013·Journal of Virology·Martijn A LangereisFrank J van Kuppeveld
Jun 8, 2012·Journal of Virology·Gemma Pérez-VilaróJuana Díez
Mar 11, 2009·Retrovirology·Christine Chable-BessiaMonsef Benkirane
Sep 10, 2010·RNA·Aline MarnefNancy Standart
Feb 9, 2010·PloS One·Vyacheslav FurtakDerya Unutmaz
Mar 3, 2010·PLoS Pathogens·Bryan R Cullen
Dec 14, 2011·Viruses·Hilda Montero, Vicenta Trujillo-Alonso
Mar 23, 2013·Viruses·Eun-Gyung LeeMaxine L Linial
Jun 28, 2011·Future Virology·Karen Chiang, Andrew P Rice

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.