PMID: 8585990Nov 1, 1995Paper

P1 clones from Drosophila melanogaster as markers to study the chromosomal evolution of Muller's A element in two species of the obscura group of Drosophila

Chromosoma
C SegarraD L Hartl

Abstract

Thirty P1 clones from the X chromosome (Muller's A element) of Drosophila melanogaster were cross-hybridized in situ to Drosophila subobscura and Drosophila pseudoobscura polytene chromosomes. An additional recombinant phage lambda Dsuby was also used as a marker. Twenty-three (77%) of the P1 clones gave positive hybridization on D. pseudoobscura chromosomes but only 16 (53%) did so with those of D. subobscura. Eight P1 clones gave more than one hybridization signal on D. pseudoobscura and/or D. subobscura chromosomes. All P1 clones and lambda Dsuby hybridized on Muller's A element (X chromosome) of D. subobscura. In contrast, only 18 P1 clones and lambda Dsuby hybridized on Muller's A element (XL chromosomal arm) of D. pseudoobscura; 4 additional P1 clones hybridized on Muller's D element (XR chromosomal arm) of this species and the remaining P1 clone gave one hybridization signal on each arm of the X chromosome. This latter clone may contain one breakpoint of a pericentric inversion that may account for the interchange of genetic material between Muller's A and D elements in D. pseudoobscura. In contrast to the rare interchange of genetic material between chromosomal elements, profound differences in the order and spacing of ...Continue Reading

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Citations

Jun 3, 2005·Genome Research·Josefa GonzálezAlfredo Ruiz
Mar 21, 2006·Genetics·Carolina Bartolomé, Brian Charlesworth
Oct 10, 2006·Genetics·Doris Bachtrog, Peter Andolfatto
Oct 10, 2006·Genetics·Josefa GonzálezAlfredo Ruiz
Jul 16, 2008·Genetics·Arjun BhutkarWilliam M Gelbart
May 24, 2001·Molecular Biology and Evolution·A MunteC Segarra
Mar 12, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Carlos F PradaAlfredo Ruiz
Jan 13, 2017·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Dorcas J OrengoMontserrat Aguadé

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