P3: Phylogenetic Posterior Prediction in RevBayes

Molecular Biology and Evolution
Sebastian HöhnaJeremy M Brown


Tests of absolute model fit are crucial in model-based inference because poorly structured models can lead to biased parameter estimates. In Bayesian inference, posterior predictive simulations can be used to test absolute model fit. However, such tests have not been commonly practiced in phylogenetic inference due to a lack of convenient and flexible software. Here, we describe our newly implemented tests of model fit using posterior predictive testing, based on both data- and inference-based test statistics, in the phylogenetics software RevBayes. This new implementation makes a large spectrum of models available for use through a user-friendly and flexible interface.


Feb 1, 1993·Journal of Molecular Evolution·N Goldman
Jun 1, 1997·Computer Applications in the Biosciences : CABIOS·A Rambaut, N C Grassly
Dec 18, 2001·Science·J P HuelsenbeckJ P Bollback
Jun 26, 2002·Molecular Biology and Evolution·Jonathan P Bollback
Feb 13, 2004·Bioinformatics·Gautam AltekarFredrik Ronquist
Dec 23, 2008·Bioinformatics·Jeremy M Brown, Robert ElDabaje
Feb 24, 2012·Systematic Biology·Fredrik RonquistJohn P Huelsenbeck
Aug 1, 2012·Nature Methods·Diego DarribaDavid Posada
Jul 3, 2013·Molecular Biology and Evolution·Jonathan RomiguierEmmanuel J P Douzery
Feb 25, 2014·Systematic Biology·Jeremy M Brown
Jun 22, 2014·Systematic Biology·Sebastian HöhnaJohn P Huelsenbeck
Jun 24, 2015·Systematic Biology·Vinson P DoyleJeremy M Brown
Mar 24, 2017·Molecular Biology and Evolution·David A DuchêneSimon Y W Ho

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