p53 and Metabolism: The GAMT Connection

Molecular Cell
Yan Zhu, Carol Prives

Abstract

In this issue of Molecular Cell, Ide et al. (2009) have identified the enzyme guanidinoacetate methyltransferase (GAMT) that regulates creatine metabolism as a p53 target involved in apoptosis, reactive oxygen species (ROS), and fatty acid metabolism.

References

Aug 28, 2007·Cell·Yael Aylon, Moshe Oren
May 5, 2009·Cell·Karen H Vousden, Carol Prives
Sep 18, 2009·Nature Reviews. Cancer·Karen H Vousden, Kevin M Ryan

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Citations

Nov 5, 2013·Cancer Biology & Therapy·Olga V LeontievaMikhail V Blagosklonny
Jan 1, 2014·Cancer Letters·Juan LiuZhaohui Feng
Apr 7, 2018·Molecular Oncology·Tobias FurlanJakob Troppmair
Nov 21, 2009·Journal of Applied Physiology·Akshay Sood
Oct 18, 2019·Expert Opinion on Drug Discovery·Miroslava Cuperlovic-Culf, Amanpreet Badhwar

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