PMID: 9192545Jan 1, 1997Paper

p53 In biopsies of oral squamous cell carcinoma. A comparative study with a malignancy grading system

Oral Oncology
V C De AraújoN S De Araújo

Abstract

The relationship between the histological grading of malignancy and p53 protein expression was studied in 40 biopsies of oral squamous cell carcinomas. An immunohistochemical analysis was carried out using the streptavidin method preceded by a treatment with citric acid in a microwave oven. All cases were classified according to the histological malignancy grading system proposed by Anneroth et al. (Scandinavian Journal of Dental Research 1987, 95, 229-249). The expression of p53 was found in 62.5% of the carcinomas studied. Positivity of p53 staining showed a correlation with the histological grade of malignancy and with the degree of keratinisation, nuclear polymorphism and number of mitoses.

References

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Citations

Sep 1, 2009·Journal of Maxillofacial and Oral Surgery·Bhushan V JayadeAswari Sant
Jun 18, 2004·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Chung-Ji LiuYong-Kie Wong
Aug 22, 2006·Journal of Cutaneous Pathology·Dalva Regina Neto PimentelLuc Weckx
May 20, 2016·Journal of Oral and Maxillofacial Pathology : JOMFP·Kajal V DaveTapan G Modi
Nov 6, 2015·Journal of Applied Oral Science : Revista FOB·Pritam Kumar MankapureManda Mandale
Jul 3, 2013·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·José de Assis Silva JúniorSimone Queiroz Chaves Lourenço
Sep 13, 2002·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Cristiane Helena SquarizeDécio Santos Pinto

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