journal cover

PacBio library preparation using blunt-end adapter ligation produces significant artefactual fusion DNA sequences

bioRxiv

Jan 9, 2018

Paul M GriffithXiaolin Wu

Abstract

Pacific Biosciences (PacBio) RS II sequencer, utilizing Single-Molecule, Real-Time (SMRT) technology, has revolutionized next-generation sequencing by providing an accurate long-read platform. PacBio single-molecule long reads have been used to delineate complex spliceoforms, detect mut...read more

Mentioned in this Paper

NCOR2 wt Allele
Genome
Complex (molecular entity)
Chimera Organism
Hairpin Loop Sequence
Nucleic Acid Sequencing
Adverse Event
Sequencing
Massively-Parallel Sequencing
Adaptation
44
1
7
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Genomic Techniques (Preprints)

Recent developments in genomics and further development of advanced post-genomic technologies, it will be possible to apply a more holistic analysis to genomic analysis. Discover the latest preprints in genomic techniques.

Chromosomal Translocation

Chromosomal Translocation occur when regions on two chromosomes breaks and swaps places or when a region is attached to another chromosome. Discover the latest research on Chromosomal Translocation here.

© 2020 Meta ULC. All rights reserved

PacBio library preparation using blunt-end adapter ligation produces significant artefactual fusion DNA sequences

bioRxiv

Jan 9, 2018

Paul M GriffithXiaolin Wu

PMID: 990245241

DOI: 10.1101/245241

Abstract

Pacific Biosciences (PacBio) RS II sequencer, utilizing Single-Molecule, Real-Time (SMRT) technology, has revolutionized next-generation sequencing by providing an accurate long-read platform. PacBio single-molecule long reads have been used to delineate complex spliceoforms, detect mut...read more

Mentioned in this Paper

NCOR2 wt Allele
Genome
Complex (molecular entity)
Chimera Organism
Hairpin Loop Sequence
Nucleic Acid Sequencing
Adverse Event
Sequencing
Massively-Parallel Sequencing
Adaptation
44
1
7

Similar Papers Found In These Feeds

BioRxiv Preprints

BioRxiv is the preprint server for biology, operated by Cold Spring Harbor Laboratory. Here are the latest biology preprint articles from bioRxiv.

Genomic Techniques (Preprints)

Recent developments in genomics and further development of advanced post-genomic technologies, it will be possible to apply a more holistic analysis to genomic analysis. Discover the latest preprints in genomic techniques.

Related Papers

Methods in Molecular Biology

Identification of DNA Base Modifications by Means of Pacific Biosciences RS Sequencing Technology

Methods in Molecular BiologyNovember 15, 2017
Philip KelleherDouwe van Sinderen
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
/papers/pacbio-library-preparation-using-blunt-end/990245241