Pacemaker malfunction associated with proton beam therapy: a report of two cases and review of literature-does field-to-generator distance matter?

Oxford Medical Case Reports
Tomoko UeyamaYoshio Hishikawa

Abstract

It is well known that radiotherapy causes malfunctions of cardiac implantable electronic devices such as pacemaker (PM) and implantable cardioverter-defibrillator because of incidental neutron production. Here, we report our experience with two cases of PM reset among seven patients with PM who underwent proton beam therapy (PBT) from January 2011 to April 2015 at our centre. Our experience shows PM reset can occur also with abdominal PBT. In both cases, PM reset was not detected by electrocardiogram (ECG) monitoring but was rather discovered by post-treatment programmer analysis. Our cases suggest that PM malfunction may not always be detected by ECG monitoring and emphasize the importance of daily programmer analysis.

References

Apr 28, 2007·Pacing and Clinical Electrophysiology : PACE·Jan Nemec
Jun 10, 2008·International Journal of Radiation Oncology, Biology, Physics·Yoshiko OshiroKoichi Tokuuye
Aug 13, 2013·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Tomas ZarembaSam Riahi
Oct 1, 2013·International Journal of Radiation Oncology, Biology, Physics·Daniel R GomezAnne H Dougherty

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Citations

Apr 6, 2019·Australasian Physical & Engineering Sciences in Medicine·Hossein AslianMara Severgnini
Apr 13, 2021·International Journal of Radiation Oncology, Biology, Physics·Henrik Laurits BjerreCamilla Jensenius Skovhus Kronborg
Nov 16, 2021·Japanese Journal of Radiology·Takayuki HashimotoUNKNOWN Japan Radiological Society multi-institutional study group

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