Pacinian Corpuscles in a Cervical Chondrocutaneous Remnant: A Case Report and Update of Pacinian Corpuscles

The American Journal of Dermatopathology
Jorge FeitoJ A Vega

Abstract

Cervical chondrocutaneous remnants are congenital, benign, and rare neck masses. We present here for the first time the immunohistochemical profile of Pacinian corpuscles present in cervical chondrocutaneous remnants, removed, and localized in the territory of the second branchial arch from a 5-year-old girl. We have performed immunohistochemistry to analyze these sensory corpuscles using a battery of antibodies including markers for each corpuscle constituent. The central axon was immunoreactive for neurofilaments, neuron-specific enolase, and neural cell adhesion molecule; the Schwann-related cells forming the inner core displayed immunoreactivity for S100 protein, vimentin, and neural cell adhesion molecule; the outer core and the capsule were positive for vimentin, epithelial membrane antigen, and glucose transporter 1. These results are discussed in topographical differences. Moreover, a brief update about the structure, protein composition, and development of Pacinian corpuscles was performed.

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Citations

Apr 20, 2017·International Journal of Surgical Pathology·Sanjay A Pai
Feb 7, 2017·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·J García-PiquerasJ Feito
Aug 31, 2020·Journal of Anatomy·Ramón CoboJosé A Vega
Oct 1, 2020·Journal of Anatomy·Yolanda García-MesaJosé A Vega
Dec 24, 2019·Journal of Anatomy·Jorge García-PiquerasJosé A Vega
Aug 31, 2020·Auris, Nasus, Larynx·Tatsuya IshigakiNobuyuki Mitsukawa
Jan 14, 2021·Journal of Clinical Medicine·Ramón CoboJosé A Vega
Feb 1, 2019·Annals of Dermatology·Sang-Jin CheonHyang-Suk You

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