Paediatric constipation for adult surgeons--article 1: targeting the cause

ANZ Journal of Surgery
Jonathan R SutcliffeJ M Hutson

Abstract

Constipation is very common in all age groups and can be resistant to standard therapies, producing chronic morbidity. Childhood onset constipation frequently produces symptoms that persist into adulthood. Recent advances have been made in the diagnosis and treatment of childhood constipation that could have application in adult practice. In the first part of the present review, the methods of differentiation of patients with a disorder of colonic motility from those with an anorectal hold-up are discussed. Slow transit constipation, with distinct features on colonic manometry and scintigraphy, has only recently been recognized in children. This diagnosis, together with a novel method of placement of a manometric catheter, is described. While the cause of slow transit constipation remains unclear, clinical features that differ between children and adults may provide an insight into the aetiology. The diagnosis of intestinal neuronal dysplasia is explained and the controversy surrounding the diagnosis outlined. We propose that the traditional histological criteria exclude many other clinically significant forms of dysplasia of the enteric nervous system and should be extended.

References

May 1, 1992·The Journal of Pediatrics·C Di LorenzoP E Hyman
Jul 1, 1991·Journal of Pediatric Gastroenterology and Nutrition·A Bautista CasasnovasR Tojo Sierra
Mar 1, 1990·Gastroenterology·G BazzocchiW J Snape
Apr 1, 1989·Digestive Diseases and Sciences·A Sonnenberg, T R Koch
Jan 1, 1989·Diseases of the Colon and Rectum·A Sonnenberg, T R Koch
Jun 1, 1985·Journal of Pediatric Surgery·K MunakataH Sueoka
Nov 1, 1981·Diseases of the Colon and Rectum·P ArhanD Pellerin
Jan 1, 1995·Virchows Archiv : an International Journal of Pathology·W A Meier-RugeF Stoss
Feb 1, 1995·Seminars in Pediatric Surgery·D P Ryan
Nov 1, 1993·Gastroenterology·V Loening-Baucke
May 1, 1993·Diseases of the Colon and Rectum·M E PezimS F Phillips
Oct 1, 1995·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·P P SchmittenbecherB Wiebecke
Aug 1, 1996·The Australian and New Zealand Journal of Surgery·C PlatellR Stitz
Oct 1, 1996·Journal of Pediatric Gastroenterology and Nutrition·M A BenningaJ A Taminiau
Jan 1, 1997·Pathology, Research and Practice·W A Meier-Ruge, C H Longo-Bauer
Oct 15, 1998·The New England Journal of Medicine·G IaconoA Carroccio
Oct 15, 1998·The New England Journal of Medicine·V Loening-Baucke
Nov 5, 1998·Journal of Clinical Gastroenterology·A Kaul, C D Rudolph
Mar 20, 1999·The New England Journal of Medicine·S DaherM B de Morais
Jul 16, 1999·The American Journal of Gastroenterology·G BassottiC R Bilder
Mar 20, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·S S RaoK Ackerson
Jan 31, 2002·Journal of Pediatric Surgery·G MartuccielloV Jasonni
Mar 12, 2002·Journal of Paediatrics and Child Health·J M HutsonY M Shin
May 1, 2002·Annals of Surgery·Mark S CohenJeffrey F Moley
Dec 17, 2002·Journal of Pediatric Surgery·Yeon Myung ShinJohn M Hutson
Feb 27, 2003·Child: Care, Health and Development·E Procter, P Loader
Aug 2, 2003·Gastroenterology·Rijk van GinkelMarc A Benninga
Aug 30, 2003·BMJ : British Medical Journal·Michael A Kamm

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Citations

May 19, 2009·Pediatric Surgery International·Melanie C C ClarkeBridget R Southwell
Oct 1, 2004·ANZ Journal of Surgery·Sebastian K KingBridget R Southwell
Feb 19, 2008·Journal of Pediatric Surgery·Melanie C C ClarkeBridget R Southwell
Dec 13, 2005·Journal of Pediatric Surgery·Sebastian K KingJohn M Hutson
Feb 13, 2015·Pediatric Surgery International·John M HutsonBridget R Southwell

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