Paediatricians' opinions of microneedle-mediated monitoring: a key stage in the translation of microneedle technology from laboratory into clinical practice

Drug Delivery and Translational Research
Karen MooneyRyan F Donnelly

Abstract

Microneedle (MN) arrays could offer an alternative method to traditional drug delivery and blood sampling methods. However, acceptance among key end-users is critical for new technologies to succeed. MNs have been advocated for use in children and so, paediatricians are key potential end-users. However, the opinions of paediatricians on MN use have been previously unexplored. The aim of this study was to investigate the views of UK paediatricians on the use of MN technology within neonatal and paediatric care. An online survey was developed and distributed among UK paediatricians to gain their opinions of MN technology and its use in the neonatal and paediatric care settings, particularly for MN-mediated monitoring. A total of 145 responses were obtained, with a completion response rate of 13.7 %. Respondents believed an alternative monitoring technique to blood sampling in children was required. Furthermore, 83 % of paediatricians believed there was a particular need in premature neonates. Overall, this potential end-user group approved of the MN technology and a MN-mediated monitoring approach. Minimal pain and the perceived ease of use were important elements in gaining favour. Concerns included the need for confirmation of ...Continue Reading

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Citations

Jun 11, 2016·Journal of Drug Targeting·Hye-Rin JeongJung-Hwan Park
Aug 4, 2016·Expert Opinion on Drug Delivery·Raghu Raj Thakur SinghRyan F Donnelly
May 17, 2017·Drug Delivery and Translational Research·Helen L QuinnRyan F Donnelly
Sep 5, 2021·Drug Delivery and Translational Research·Erkan AzizogluMark R Prausnitz

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