Pain, agitation, and behavioural problems in people with dementia admitted to general hospital wards: a longitudinal cohort study

Pain
Elizabeth L SampsonLouise Jones

Abstract

Pain is underdetected and undertreated in people with dementia. We aimed to investigate the prevalence of pain in people with dementia admitted to general hospitals and explore the association between pain and behavioural and psychiatric symptoms of dementia (BPSD). We conducted a longitudinal cohort study of 230 people, aged above 70, with dementia and unplanned medical admissions to 2 UK hospitals. Participants were assessed at baseline and every 4 days for self-reported pain (yes/no question and FACES scale) and observed pain (Pain Assessment in Advanced Dementia scale [PAINAD]) at movement and at rest, for agitation (Cohen-Mansfield Agitating Inventory [CMAI]) and BPSD (Behavioural Pathology in Alzheimer Disease Scale [BEHAVE-AD]). On admission, 27% of participants self-reported pain rising to 39% on at least 1 occasion during admission. Half of them were able to complete the FACES scale, this proportion decreasing with more severe dementia. Using the PAINAD, 19% had pain at rest and 57% had pain on movement on at least 1 occasion (in 16%, this was persistent throughout the admission). In controlled analyses, pain was not associated with CMAI scores but was strongly associated with total BEHAVE-AD scores, both when pain was...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Jan 1, 1992·International Psychogeriatrics·J Cohen-MansfieldP Werner
Dec 15, 1990·Annals of Internal Medicine·S K InouyeR I Horwitz
May 1, 1989·Journal of Gerontology·J Cohen-MansfieldA S Rosenthal
Sep 1, 1987·Journal of General Internal Medicine·M E Charlson
May 1, 1993·Journal of the American Geriatrics Society·E A Sengstaken, S A King
Apr 16, 1998·The Clinical Journal of Pain·K A HerrD Wagenaar
Oct 16, 1999·International Journal of Geriatric Psychiatry·J Cohen-Mansfield, P Werner
Jun 17, 2003·Journal of the American Medical Directors Association·Victoria WardenLadislav Volicer
Feb 6, 2004·General Hospital Psychiatry·Jouko V LaurilaReijo S Tilvis
Mar 11, 2004·Journal of Pain and Symptom Management·S José ClossKate Seers
Sep 8, 2004·International Journal of Geriatric Psychiatry·Jiska Cohen-Mansfield, Alexander Libin
Apr 20, 2005·PharmacoEconomics·Daniel L Murman, Christopher C Colenda
Jun 4, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Sophie PautexGabriel Gold
Jun 18, 2005·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·Christine R KovachThelma Wells
Jul 5, 2005·Journal of Palliative Medicine·Joseph W ShegaGreg A Sachs
Apr 18, 2006·Journal of Gerontological Nursing·Christine R KovachThelma Wells
Jan 3, 2007·Journal of the American Geriatrics Society·Joseph W ShegaGreg A Sachs
Jul 4, 2007·International Journal of Geriatric Psychiatry·Martin SteinbergUNKNOWN Cache County Investigators
Nov 21, 2008·International Psychogeriatrics·Joukje M OostermanErik J A Scherder
May 5, 2009·Pain·Erik ScherderStefan Lautenbacher
Jul 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Elizabeth L SampsonMichael King
Apr 7, 2010·The Journal of Clinical Psychiatry·Mark E KunikRobert O Morgan
Jul 24, 2010·International Journal of Geriatric Psychiatry·Alice JordanJohn T O'Brien
Nov 26, 2010·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Yukari TakaiAkiko Honda
Feb 11, 2011·International Journal of Geriatric Psychiatry·B S HuseboD Aarsland
Apr 1, 2011·Journal of the American Medical Directors Association·Shinya IshiiDebra Saliba
Jul 9, 2011·Palliative Medicine·Alice JordanJulian C Hughes
Sep 6, 2011·Age and Ageing·Sarah E GoldbergUNKNOWN Medical Crises in Older People Study Group
Oct 1, 2011·International Journal of Geriatric Psychiatry·Ladislav VolicerJenny T Van der Steen
Oct 19, 2011·BMC Geriatrics·Sharon ScottElizabeth L Sampson
Jun 19, 2012·Journal of the American Geriatrics Society·Christina Jensen-DahmGunhild Waldemar
May 9, 2014·International Journal of Geriatric Psychiatry·B S HuseboD Aarsland

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Citations

Jan 27, 2016·Neuroscience·Charles J VierckRonald G Wiley
Dec 23, 2015·Journal of the American Geriatrics Society·Fabio GuerrieroMarco Rollone
Sep 28, 2015·Journal of the American Medical Directors Association·Tessa van der MaadenRaymond T C M Koopmans
Jan 13, 2016·Journal of Alzheimer's Disease : JAD·Alba MalaraVincenzo Rispoli
Mar 12, 2016·BMC Palliative Care·Nuriye KupeliLouise Jones
Mar 29, 2016·International Journal of Geriatric Psychiatry·Nicola WhiteElizabeth L Sampson
Jul 28, 2016·Dementia·Elizabeth HansonDebbie Tolson
Jan 30, 2018·Nursing Older People·Sharron Tolman, Karen Harrison Dening
Oct 10, 2019·Pharmacotherapy·Tesfahun C EshetieLisa M Kalisch Ellett
Oct 27, 2017·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Krista L LanctôtBrendon Boot
Jun 26, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Myuri RuthirakuhanNathan Herrmann
Oct 24, 2019·Zeitschrift für Gerontologie und Geriatrie·Stelios ZygourisMagda Tsolaki
Aug 30, 2020·Journal of Clinical Nursing·Britany WalshKathleen F Hunter
Nov 20, 2016·European Journal of Pain : EJP·A HaminaS Hartikainen
Mar 25, 2017·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rachael E DockingPat A Schofield
Jun 28, 2018·International Journal of Geriatric Psychiatry·Carole FoggJackie Bridges
Jul 28, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K S FrederiksenG Waldemar
Nov 24, 2016·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rollin WrightDebra K Weiner
Dec 24, 2017·Journal of the American Geriatrics Society·Francesca L La FrenaisElizabeth L Sampson
Aug 18, 2018·Frontiers in Neurology·Wenke GrönheitJörg Wellmer
Apr 10, 2019·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Leonardo MarchiniAdina Jucan
Mar 12, 2019·International Psychogeriatrics·Milena AnatchkovaMyrlene Sanon Aigbogun
Sep 29, 2020·Frontiers in Neurology·Damiana ScuteriPaolo Tonin
May 8, 2018·Journal of Korean Academy of Nursing·Jeong Eun Yang, Gwi Ryung Son Hong
Oct 24, 2019·PloS One·Elizabeth L SampsonGerard Leavey
Feb 23, 2017·Journal of Alzheimer's Disease : JAD·Marcello IencaTenzin Wangmo
Mar 10, 2018·Current Medicinal Chemistry·Damiana ScuteriLuigi Antonio Morrone
Aug 31, 2018·Age and Ageing·Alexandra R FeastElizabeth L Sampson
Feb 15, 2019·International Journal of Geriatric Psychiatry·Jonas ReinoldFederica E Pisa

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Software Mentioned

AD
PAINAD
BEHAVE

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