PMID: 1183584Sep 1, 1975Paper

[Pain-alleviating action of fentanyl and pentazocine in combination with droperdol and carbidine].

Farmakologiia i toksikologiia
G V Novikova, E V Zorian

Abstract

Tests staged on rabbits showd that analgesic (phentanyl and pentasocine), neuroleptics (droperidol and carbidine) and their combinations produce a more pronounced and analgesic action with an electric irritation of the dental tissues than with that of the rabbit's paw. Neuroleptanalgesic mixtures containing pentasocine display a somewhat weaker analgesic activity, but their effect lasts longer and they have a less marked influence on the respiration. Mixtures containing cabidine in lieu of droperidol produce a somewhat greater analgesic effect and relax and skeletal muscles less.

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