PMID: 8607754Apr 1, 1996Paper

Pain and depression in acute traumatic spinal cord injury: origins of chronic problematic pain?

Archives of Physical Medicine and Rehabilitation
D M CairnsM D Scott

Abstract

To examine the relationship between pain and depression over time during acute phases of traumatic spinal cord injury (SCI). Theoretical models of the pain-depression relationship provided the framework: (1) pain causes depression; (2) depression causes pain; (3) pain and depression are independent sequelae to SCI. Understanding the pain-depression relationship provides treatment implications and hypotheses for origins of chronic pain in SCI. A repeated measures design assessing subjects at admission and discharge from rehabilitation. Subjects were admitted to a large public hospital in Southern California which is a member of the Model Spinal Cord Injury System. Rehabilitation occurred on two 30-bed units. Complete admission and discharge data sets were collected from 68 acute traumatic SCI patients who served as subjects. One hundred twenty-one patients initially agreed to participate in a larger study of adjustments to SCI. Thirty-three did not have pain data at admission, 16 dropped out, and 4 had incomplete discharge data. Subjects volunteered and were paid a fee. A standard rehabilitation program for SCI. Pain assessment used a 101-point numerical rating scale. Depression assessment used the Center for Epidemiological Stu...Continue Reading

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Citations

Jul 9, 2008·European Journal of Clinical Pharmacology·Thrasivoulos G TzellosDimitrios Kouvelas
Aug 4, 2011·Journal of Neurology·Dimitrios Papadopoulos, Dimos Dimitrios Mitsikostas
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Jan 23, 2015·Frontiers in Molecular Neuroscience·Ryan S TonkinGila Moalem-Taylor

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