Pain control after simultaneous bilateral total knee arthroplasty: a randomized controlled trial comparing periarticular injection and epidural analgesia

The Journal of Bone and Joint Surgery. American Volume
Sachiyuki TsukadaAkiho Hoshino

Abstract

Periarticular injection is becoming more commonly utilized for pain relief following total knee arthroplasty. However, we are aware of no randomized controlled trial that has investigated the efficacy of periarticular injection for pain relief after simultaneous bilateral total knee arthroplasty. We performed a randomized controlled trial of patients scheduled for simultaneous bilateral total knee arthroplasty. Seventy-one patients with 142 involved knees were randomly assigned to receive periarticular injection or epidural analgesia. Other perioperative interventions, including spinal anesthesia, surgical techniques, and postoperative medication protocols, were identical for all patients. The primary outcome was postoperative pain at rest, measured with the use of a 100-mm visual analog scale (VAS) during the initial twenty-four-hour postoperative period. The cumulative VAS score was calculated with use of the area under the curve and compared between the groups. Postoperative pain at rest, quantified as the area under the curve of serial assessments during the initial twenty-four-hour postoperative period, was significantly less in the periarticular injection group than in the epidural analgesia group (174.9 ± 181.5 mm × day ...Continue Reading

References

Jun 5, 2001·Anesthesiology·S S Liu, S B McDonald
Jan 6, 2009·The Journal of Bone and Joint Surgery. American Volume·Joseph MarinoJacques E Chelly
Feb 2, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·In Jun KohTae Kyun Kim
Dec 14, 2011·The Journal of Bone and Joint Surgery. American Volume·John P MeehanRichard H White
Aug 31, 2012·The Journal of Bone and Joint Surgery. British Volume·D M R GibbsC N Esler
Jan 12, 2013·Acta Anaesthesiologica Scandinavica·M T PitkänenJ G Förster
Mar 22, 2013·Clinical Orthopaedics and Related Research·Arnaud ChaumeronPascal-André Vendittoli
Aug 24, 2013·The Journal of Bone and Joint Surgery. American Volume·Susan M OdumKevin J Bozic

❮ Previous
Next ❯

Citations

May 26, 2017·Knee Surgery & Related Research·Yong Seuk Lee
Apr 10, 2017·The Journal of Arthroplasty·Sachiyuki TsukadaMotohiro Wakui
Jun 26, 2018·Clinical Orthopaedics and Related Research·Naoyuki HirasawaSachiyuki Tsukada
Sep 22, 2018·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Sachiyuki TsukadaNaoyuki Hirasawa
Mar 20, 2020·Journal of Orthopaedic Surgery and Research·Ai-Lan CaiGeng Liu
Mar 16, 2017·The Journal of Bone and Joint Surgery. American Volume·Daniel KoehlerMichael Willey
Jul 10, 2018·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Vasileios SoranoglouThomas P Sculco
Mar 19, 2020·Clinical Orthopaedics and Related Research·Hyoung-Seok JungJae Sung Lee
Jan 23, 2016·The Journal of Bone and Joint Surgery. American Volume·Gwo-Chin Lee
Nov 3, 2020·Indian Journal of Orthopaedics·Nikhil Joseph MartinJohny Joseph Pindis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.