Pain interference and catastrophizing are not associated with polysubstance use among treatment-seeking patients with substance use disorders and chronic pain.

The American Journal of Drug and Alcohol Abuse
Victoria R VotawR Kathryn McHugh

Abstract

Background: People with substance use disorders (SUD) and co-occurring chronic pain report the use of myriad substances, which is concerning due to the heightened risk of overdose associated with polysubstance use. Identifying malleable factors associated with polysubstance use in this population can inform interventions. In this study, we examined whether two pain processes - pain interference and pain catastrophizing - were associated with polysubstance use. Objectives: We examined the cross-sectional associations among self-reported pain interference and catastrophizing and polysubstance use. We also determined if sex and primary SUD moderated these associations. Methods: Participants were 236 (36% female) adults receiving inpatient treatment for SUD (58% alcohol use disorder, 42% opioid use disorder) who met criteria for chronic pain. We utilized negative binomial regression to examine associations between pain interference and catastrophizing (focal independent variables) and the number of substances used in the month before treatment (i.e., polysubstance use; outcome). Results: Participants used three substances, on average, in the month prior to treatment. Neither pain interference (IRR = 1.05, p = .06) nor pain catastro...Continue Reading

References

Jul 18, 2009·The Journal of Clinical Psychiatry·Declan T BarryRichard S Schottenfeld
Aug 29, 2009·The Journal of Pain : Official Journal of the American Pain Society·Joseph L Riley, Christopher King
Jan 17, 2012·The American Journal of Drug and Alcohol Abuse·Prasanthi NattalaLinda B Cottler
Aug 18, 2012·Journal of Substance Abuse Treatment·John S CacciolaJames R McKay
Aug 13, 2013·Postgraduate Medicine·Jeffrey A GudinSandra D Comer
May 24, 2014·Current Opinion in Psychiatry·Jason P ConnorAdrian B Kelly
Mar 15, 2015·Clinical Psychology Review·Emily L ZaleJoseph W Ditre
Jul 23, 2016·The American Journal of Psychiatry·Carlos BlancoMark Olfson
Sep 2, 2017·Cannabis and Cannabinoid Research·Kevin P HillJoseph W Ditre
Mar 20, 2018·Drug and Alcohol Dependence·Katherine A McDermottJesse R Cougle
May 15, 2018·The Journal of Pain : Official Journal of the American Pain Society·Kevin E VowlesMark D Sullivan
Aug 25, 2018·Addictive Behaviors·Victoria R VotawR Kathryn McHugh
Aug 31, 2018·Journal of Addiction Medicine·Anne C FernandezAmy S B Bohnert
Mar 14, 2019·The American Journal of Drug and Alcohol Abuse·Emily L ZaleJoseph W Ditre
Apr 26, 2019·The American Journal of Drug and Alcohol Abuse·Elizabeth T KneelandR Kathryn McHugh
May 8, 2019·Substance Use & Misuse·Victoria R VotawKatie Witkiewitz
Nov 13, 2019·Drug and Alcohol Dependence·Katherine A McDermottRoger D Weiss

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Citations

Nov 15, 2020·Molecular Psychiatry·Wilson M ComptonRobert L DuPont

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