Pain management of musculoskeletal injuries in children: current state and future directions

Pediatric Emergency Care
Samina AliSuzanne Beno

Abstract

Pain is the most common reason for seeking health care in the Western world and is a contributing factor in up to 80% of all emergency department (ED) visits. In the pediatric emergency setting, musculoskeletal injuries are one of the most common painful presentations. Inadequate pain management during medical care, especially among very young children, can have numerous detrimental effects. No standard of care exists for the management of acute musculoskeletal injury-related pain in children. Within the ED setting, pain from such injuries has been repeatedly shown to be undertreated. Upon completion of this CME article, the reader should be better able to (1) distinguish multiple nonpharmacological techniques for minimizing and treating pain and anxiety in children with musculoskeletal injuries, (2) apply recent medical literature in deciding pharmacological strategies for the treatment of children with musculoskeletal injuries, and (3) interpret the basic principles of pharmacogenomics and how they relate to analgesic efficacy. Pediatric musculoskeletal injuries are both common and painful. There is growing evidence that, in addition to pharmacological therapy, nonpharmacological methods can be introduced to improve analgesia...Continue Reading

References

Dec 1, 1989·British Journal of Clinical Pharmacology·Q Y YueJ Säwe
Oct 15, 1988·Lancet·H White
Oct 15, 1988·Lancet·Z R ChenF Bochner
Feb 1, 1994·Annals of Emergency Medicine·L R Friedland, R M Kulick
Apr 1, 1997·Pediatric Emergency Care·L R FriedlandK M Duncan
Apr 1, 1997·Clinical Pharmacology and Therapeutics·G MikusM Eichelbaum
Apr 1, 1997·Journal of Pediatric Orthopedics. Part B·L A Landin
Jan 1, 1997·European Journal of Clinical Pharmacology·J HasselströmJ Säwe
Dec 31, 1997·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·B Ngai, J Ducharme
Mar 10, 1998·Archives of Pediatrics & Adolescent Medicine·S J WeismanN L Schechter
May 27, 1999·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·P Tanabe, M Buschmann
Aug 18, 1999·British Journal of Sports Medicine·G O'Toole, S Rayatt
Oct 26, 1999·Issues in Comprehensive Pediatric Nursing·M E MegelL S Gleaves
Apr 18, 2002·Journal of Emergency Nursing : JEN : Official Publication of the Emergency Department Nurses Association·Paula TanabeRichard Marcantonio
May 7, 2002·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·J O'DonnellT F Beattie
May 7, 2002·The American Journal of Emergency Medicine·William H CordellEdward J Brizendine
Jul 9, 2002·Journal of Clinical Nursing·Tarja PölkkiAnna-Maija Pietilä
Jul 10, 2002·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Mustafa OncelNecmi Kurt
Jul 29, 2003·Annals of Emergency Medicine·Julie C BrownPeter Cummings
Aug 6, 2003·Annals of Emergency Medicine·Thomas D Wendel
Dec 4, 2003·European Journal of Clinical Investigation·U I Schwarz
Feb 3, 2004·The American Journal of Sports Medicine·Chris BleakleyDomhnall MacAuley
Nov 13, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Cyrus CooperTjeerd P van Staa
Dec 21, 2004·British Journal of Clinical Pharmacology·Carmen MartínezJosé A G Agúndez
Jan 25, 2005·British Journal of Sports Medicine·P Wheeler, M E Batt
May 26, 2005·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·C Celeste JohnstonPatricia Bourgault
Aug 4, 2005·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Ewa IdvallIngrid Runeson
Aug 23, 2005·Emergency Medicine Journal : EMJ·Simon Clarke, Fiona Lecky
Jan 4, 2006·Archives of Pediatrics & Adolescent Medicine·Russell T MigitaMichelle M Garrison
Feb 17, 2006·Pediatric Emergency Care·Amy L DrendelMichael K Kim
May 2, 2006·Molecular Diagnosis & Therapy·Elena García-MartínJosé A G Agúndez
May 9, 2006·Jornal de pediatria·Thamine P HatemSandra S Mattos

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Citations

Nov 10, 2011·Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology·Cheol Kyu HwangHorace H Loh
Mar 20, 2013·Canadian Pharmacists Journal : CPJ = Revue Des Pharmaciens Du Canada : RPC·Cecile WongFiona Campbell
Jan 1, 2014·European Journal of Pediatrics·Pierluigi MarzuilloEgidio Barbi
Mar 13, 2014·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Katherine L Boyle, Christopher D Rosenbaum
Apr 2, 2019·Orthopaedic Nursing·Caitlin Coit, Elizabeth Shannon
Jul 2, 2015·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Graham C ThompsonUNKNOWN Pediatric Emergency Research Canada
Dec 5, 2019·Italian Journal of Pediatrics·Gian Luigi MarsegliaPaola Marchisio
Oct 31, 2017·Pediatric Emergency Care·Adrianna D M ClappAntonia Schirmer Stang
Mar 13, 2015·Evidence-based Medicine·Kevin B L Lim
Jan 13, 2017·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Lisa HartlingAmy L Drendel
Oct 20, 2018·Clinical Psychological Science : a Journal of the Association for Psychological Science·Genevieve F DashSarah W Feldstein Ewing
Oct 26, 2016·Paediatric Anaesthesia·Margaret J LivingstoneTonya M Palermo
Jul 22, 2014·Emergency Medicine Australasia : EMA·Erin MillsEd Oakley
Jul 27, 2018·Paediatrics & Child Health·Evelyne D TrottierUNKNOWN Pediatric Emergency Research Canada Pain Interest Group
Jul 16, 2015·Paediatrics & Child Health·Evelyne D TrottierJocelyn Gravel
Dec 18, 2020·The Journal of Pediatrics·Samina AliUNKNOWN Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE Team) and Pediatric Emergency Research Canada (PERC)
Sep 10, 2021·PloS One·Samina AliUNKNOWN Pediatric Emergency Research Canada

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