Pain palliation with strontium-89 in children with metastatic disease

Medical and Pediatric Oncology
M CharronJ Mirro

Abstract

We report two cases of children with metastatic bone disease who received strontium-89 intravenously. An 11-year-old boy with stage IV neuroblastoma received 50 microCi/kg of strontium-89. He had a good response, and his pain abated to the point that he could be taken off IV Dilaudid and was discharged from the hospital. A 7-year-old girl with the diagnosis of squamous cell carcinoma of the lung disclosed minimal increased uptake on a bone scan. Following the strontium-89 therapy, she did not have any significant improvement in pain, probably due to the minimal osteoblastic activity evidenced by the minimal abnormalities on the bone scan. Until this report there has been no reported case of using strontium-89 in the treatment of children with metastatic disease.

References

Jan 1, 1992·Seminars in Nuclear Medicine
Jan 1, 1992·Seminars in Nuclear Medicine·R G RobinsonK G Baxter
Jan 1, 1991·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·V J LewingtonM A Zivanovic
Mar 1, 1989·Radiographics : a Review Publication of the Radiological Society of North America, Inc·R G RobinsonD M Ackery
Apr 6, 1964·JAMA : the Journal of the American Medical Association·D M SKLAROFF, N D CHARKES

❮ Previous
Next ❯

Citations

Jun 27, 2006·Child and Adolescent Psychiatric Clinics of North America·Renée McCulloch, John J Collins
Dec 4, 2002·Medical and Pediatric Oncology·Nikos GompakisK Pistevou
Dec 18, 1998·American Journal of Clinical Oncology·T H Vishne, I G Ron
Jan 22, 1998·Medical and Pediatric Oncology·F Giammarile, P Chauvot
Sep 11, 2001·Radiologic Clinics of North America·H R Nadel, M E Stilwell

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.