Pain relief after Frey's procedure for chronic pancreatitis

The British Journal of Surgery
Sanjay NegiAdarsh Chaudhary

Abstract

Few studies have addressed long-term pain relief after Frey's procedure (local head resection with lateral pancreaticojejunostomy, LR-LPJ) for chronic pancreatitis. This retrospective study evaluated pain control using a validated score and risk factors associated with failure to achieve complete pain relief following LR-LPJ. Sixty of 134 patients with chronic pancreatitis underwent LR-LPJ and were evaluated prospectively using the Izbicki pain score before surgery, and 1, 2, 5 and 7 years later. Analysis was on an intention-to-treat basis and predictors of complete pain relief were identified by multivariable analysis. After a median follow-up of 6.4 years, the median pain score was reduced from 46.4 to 10.0 (P < 0.001) with partial or complete pain relief in 75 per cent of patients, and a significant reduction in median number of episodes requiring hospitalization (from 4 to 0; P < 0.001). Preoperative use of opiate medication (odds ratio (OR) 30.14; P = 0.015), continuous pattern of pain (OR 22.65; P = 0.025) and occurrence of postoperative complications (OR 10.52; P = 0.030) were significant predictors of failure to achieve complete pain relief after surgery. Frey's procedure leads to significant and sustained long-term pai...Continue Reading

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Citations

Mar 16, 2012·Annals of Surgery·Niels A van der GaagMarja A Boermeester
Feb 22, 2014·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·F CauchyF Paye
Jun 20, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Catherine J YangJennifer F Tseng
Jan 2, 2016·The Indian Journal of Surgery·Dilip Parekh, Sathima Natarajan
Mar 25, 2016·The Indian Journal of Surgery·A K Pujahari
Nov 7, 2016·Pediatric Surgery International·Maria G Sacco CasamassimaPaul M Colombani
Mar 23, 2017·American Journal of Surgery·John D TillouKenneth L Brayman
Sep 13, 2017·Current Treatment Options in Gastroenterology·Varvara A KirchnerMelena D Bellin
Nov 30, 2018·European Journal of Gastroenterology & Hepatology·Minas BaltatzisAjith K Siriwardena
Jul 18, 2019·Journal of Gastroenterology and Hepatology·Søren S OlesenUNKNOWN Scandinavian Baltic Pancreatic Club
Jul 4, 2019·The Clinical Journal of Pain·Louise KuhlmannAsbjørn M Drewes
Jul 13, 2017·Current Opinion in Gastroenterology·Mahya FaghihVikesh K Singh
Oct 28, 2019·Langenbeck's Archives of Surgery·A MerdrignacLaurent Sulpice
May 28, 2020·Annals of Hepato-biliary-pancreatic Surgery·Pagadala Naga Balaji NiteshDasari Varun
Jul 15, 2015·Current Opinion in Gastroenterology·Robert A MoranPankaj Jay Pasricha
Jun 10, 2020·Pediatric Surgery International·Sukanta RaySujan Khamrui
Feb 23, 2021·Scandinavian Journal of Gastroenterology·Roland AnderssonUNKNOWN Working Group for Chronic Pancreatitis Guidelines (Sweden)
Feb 21, 2021·American Journal of Surgery·Sukanta RayZuber Ansari
Feb 28, 2021·Hepatobiliary & Pancreatic Diseases International : HBPD INT·Minas BaltatzisAjith K Siriwardena

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