Pain relief for women undergoing oocyte retrieval for assisted reproduction

The Cochrane Database of Systematic Reviews
Irene KwanSiladitya Bhattacharya

Abstract

Various methods of conscious sedation and analgesia (CSA) have been used during oocyte retrieval for assisted reproduction. The choice of agent has been influenced by the quality of sedation and analgesia and by concerns about possible detrimental effects on reproductive outcomes. To assess the effectiveness and safety of different methods of conscious sedation and analgesia for pain relief and pregnancy outcomes in women undergoing transvaginal oocyte retrieval. We searched; the Cochrane Gynaecology and Fertility specialised register, CENTRAL, MEDLINE, Embase, PsycINFO and CINAHL, and trials registers in November 2017. We also checked references, and contacted study authors for additional studies. We included randomised controlled trials (RCTs) comparing different methods and administrative protocols for conscious sedation and analgesia during oocyte retrieval. We used standard methodological procedures expected by Cochrane. Our primary outcomes were intraoperative and postoperative pain. Secondary outcomes included clinical pregnancy, patient satisfaction, analgesic side effects, and postoperative complications. We included 24 RCTs (3160 women) in five comparisons. We report the main comparisons below. Evidence quality was ge...Continue Reading

References

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Citations

Aug 18, 2018·The Cochrane Database of Systematic Reviews·Cindy Farquhar, Jane Marjoribanks
Jul 31, 2019·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Shuai ZhaoYuan Zhang
Oct 21, 2020·Fertility and Sterility·Erato Terpsichori Iduna Antigoni BuismanJan Willem van der Steeg

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