Pain rewarded: hyperalgesic and allodynic effect of operant conditioning in healthy humans-protocol for a systematic review and meta-analysis

Systematic Reviews
Wacław M AdamczykPrzemysław Bąbel

Abstract

'Pain rewarded' is a hypothesis wherein acute pain sufferers are exposed to reinforcers and punishers from their environment that shape their behaviour, i.e. pain responses. Such a point of view has been taken for granted by many clinicians and researchers although existing evidence has not yet been systematically summarized. This planned systematic review and meta-analysis is aiming to summarize the research findings on pain modulation (hyperalgesic effect) and pain elicitation (allodynic effect) resulting from operant conditioning procedures in healthy humans. The systematic review will be performed by searching for articles indexed in PubMed database, Cochrane Register of Controlled Trials (CENTRAL), Web of Science™, ScienceDirect, EBSCO database, PsycINFO, MEDLINE, PsycARTICLES and CINAHL. Studies will be included if they investigate healthy humans, exposed to modulation or elicitation of a pain experience induced by operant conditioning. Studies will be screened for eligibility and risk of bias by two independent assessors. Narrative and meta-analytical syntheses are planned. Data will be pooled and analyzed qualitatively and quantitatively (if possible) in order to advance the understanding of pain mechanisms, especially ...Continue Reading

References

Apr 1, 1985·Perceptual and Motor Skills·S J Linton, K G Götestam
Dec 1, 1982·Journal of Behavioral Medicine·W E FordyceD E Dundore
Dec 1, 1996·Perceptual and Motor Skills·R LousbergA A Gielen
Jan 13, 2004·Pain·Christopher D Jolliffe, Michael K Nicholas
Apr 9, 2005·The Clinical Journal of Pain·Richel LousbergHermie Hermens
Apr 20, 2005·Pain·Rupert HölzlEllena Huse
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Jan 7, 2009·Journal of the American Board of Family Medicine : JABFM·Richard A DeyoBrook I Martin
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Aug 9, 2011·British Journal of Sports Medicine·Peter O'Sullivan
Jan 21, 2012·Current Pain and Headache Reports·Rena GatzounisJohan W S Vlaeyen
Jan 20, 2015·Pain·G Lorimer Moseley, Johan W S Vlaeyen
Mar 6, 2016·Pain·Kaya J PeerdemanAndrea W M Evers
Oct 19, 2016·Pain·Amanda C de C Williams, Kenneth D Craig

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