PMID: 9530442Apr 8, 1998Paper

Pain syndromes with causal participation of the sympathetic nervous system

Der Anaesthesist
R Baron, Wilfrid Jänig

Abstract

The efferent sympathetic nervous system is organized into subsystems that innervate and regulate via separate peripheral sympathic pathways the different autonomic target organs. This review discusses mechanisms through which this efferent system may be causally involved in the generation of pain. Clinical pain syndromes in which this may be the case are "complex regional pain syndromes" (CRPS) type I (previously reflex sympathetic dystrophy) and type II (recently causalgia). The "sympathetically maintained pain" (SMP) is a symptom (and not a clinical entity) that can principally also be present in other pain syndromes. An explanatory hypothesis, which may explain the clinical phenomenology of CRPS (different types of pain, swelling, autonomic, motor and trophic changes) and the mechanisms involved, is described and discussed. This hypothesis consists of different components that either have been tested and verified experimentally or which are still hypothetical. The hypothesis consists of changes in the primary afferent (nociceptive and non-nociceptive) neurones (sensitization, ectopic impulse generation) and of the neurones in the spinal cord (preferentially in the dorsal horn) which are secondary consequences of the changes ...Continue Reading

Citations

Jun 28, 2015·BMC Complementary and Alternative Medicine·Simon EgliLorenz Fischer
Jul 17, 2018·Journal of Back and Musculoskeletal Rehabilitation·Hüseyin NazlıkulAycel Derya Tanay Öztürk
Oct 3, 2006·Current Opinion in Anaesthesiology·B DonnerT Weiss
Nov 23, 2006·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Andre MullerR Norman Harden
Feb 6, 2007·Neurosurgery·Zoran Roganovic, Gordana Mandic-Gajic
Dec 9, 2014·Hospital Practice·Susan M MoeschlerW David Mauck
Oct 28, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ilaria SalvaggioAdriana Mascaro
Mar 17, 2001·Current Pain and Headache Reports·R Baron, G Wasner
Apr 18, 2003·Cephalalgia : an International Journal of Headache·W Jänig
Nov 29, 2011·Der Schmerz·N EgloffR von Känel
Apr 25, 2000·Journal of Clinical Anesthesia·F R ManekshaP J Poppers
Oct 24, 2003·Lancet Neurology·Wilfrid Jänig, Ralf Baron

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