Pain therapy in intensive care patients

Der Anaesthesist
Katharina Rose, Winfried Meißner

Abstract

After intensive care unit (ICU) treatment, the recollection of experienced pain is one of the most burdensome aftermaths. In addition, pain has several negative physiological consequences. The majority of patients report moderate to severe pain while being treated on an ICU, often caused by diagnostic or therapeutic procedures. Pain and its functional consequences during ICU treatment should therefore be systematically recorded and treated. Due to their high analgesic potency, pharmacological pain therapy focuses on opioids; however, gastrointestinal motility disturbance and development of tolerance are disadvantages. When applying non-opioids, such as non-steroidal anti-inflammatory drugs (NSAID) and paracetamol, attention should be paid to their possible organ toxicity. Ketamine and α2-antagonists can complement the analgesic concept. Analogous to its perioperative administration, intravenous lidocaine in intensive care seems acceptable because of a favorable impact on opioid requirements and gastrointestinal motility. When using regional anesthesia the positive therapeutic effect and the possible complications need to be carefully weighed. Non-pharmaceutical procedures, especially transcutaneous electrical nerve stimulation ...Continue Reading

References

Sep 1, 1995·Pharmacotherapy·J K WhippleR K Ausman
Jan 9, 2003·Best Practice & Research. Clinical Anaesthesiology·Christopher M Bernards
Jan 25, 2005·Brain, Behavior, and Immunity·Julie Wieseler-FrankLinda R Watkins
Apr 21, 2006·Critical Care Medicine·Gerald ChanquesJean-Jacques Eledjam
Dec 26, 2006·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Paul M SzumitaMichael E Wechsler
May 11, 2007·Best Practice & Research. Clinical Anaesthesiology·Marc F De Kock, Patricia M Lavand'homme
Dec 8, 2007·Critical Care : the Official Journal of the Critical Care Forum·Jörg MartinClaudia Spies
Mar 12, 2008·Acta Anaesthesiologica Scandinavica·O M S FredheimO Dale
Nov 3, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Miles Belgrade, Sara Hall
Aug 3, 2011·AACN Advanced Critical Care·Debra J Drew, Barbara J St Marie
Aug 13, 2011·Journal of Pain & Palliative Care Pharmacotherapy·Chitra Ramasubbu, Anita Gupta
Dec 7, 2011·Saudi Journal of Anaesthesia·Joseph D Tobias, Marc Leder
Mar 17, 2012·Critical Care : the Official Journal of the Critical Care Forum·Raquel WanzuitaGlauco Adrieno Westphal
Jan 13, 2015·Lancet Neurology·Nanna B FinnerupMark Wallace
Jun 16, 2015·The Cochrane Database of Systematic Reviews·Mark I JohnsonKathleen A Sluka
Aug 5, 2015·European Journal of Anaesthesiology·Dominique FletcherUNKNOWN euCPSP group for the Clinical Trial Network group of the European Society of Anaesthesiology
Sep 12, 2015·Current Medical Research and Opinion·Winfried MeissnerJoseph Pergolizzi
Sep 29, 2015·The Cochrane Database of Systematic Reviews·R Andrew MoorePhilip J Wiffen
Nov 26, 2015·The New England Journal of Medicine·Jane C Ballantyne, Mark D Sullivan
Jun 12, 2016·Journal of Critical Care·Jessica L ElefritzMichael R Lyaker
Oct 27, 2016·Neuroscience·Laurie-Anne RoeckelFrédéric Simonin
Aug 19, 2016·The Journal of Bone and Joint Surgery. American Volume·Thomas W HamiltonHemant G Pandit
Nov 1, 2016·Postgraduate Medical Journal·Eric EhieliSrinivas Pyati
Feb 9, 2017·Journal of Clinical Pharmacology·Yoonsun MoGeorge E Karras
Mar 18, 2017·European Journal of Anaesthesiology·Thomas StueberHans-Jörg Gillmann

❮ Previous
Next ❯

Citations

Jun 20, 2019·Minerva anestesiologica·Andrea Gentili
Apr 13, 2019·Current Pain and Headache Reports·Michal CzernickiRichard D Urman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine
Alexander BertalanffyKlaus Hoerauf
The Journal of the American Dental Association
Wayne W HermanRobert W Comer
© 2022 Meta ULC. All rights reserved