Paired-angle-rotation scanning optical coherence tomography forward-imaging probe

Optics Letters
Jigang WuChanghuei Yang

Abstract

We report a novel forward-imaging optical coherence tomography (OCT), needle-probe paired-angle-rotation scanning OCT (PARS-OCT) probe. The probe uses two rotating angled gradient-index lenses to scan the output OCT probe beam over a wide angular arc (approximately 19 degrees half-angle) of the region forward of the probe. Among other advantages, this probe design is readily amenable to miniaturization and is capable of a variety of scan modes, including volumetric scans. To demonstrate the advantages of the probe design, we have constructed a prototype probe with an outer diameter of 1.65 mm and employed it to acquire four OCT images, with a 45 degrees angle between adjacent images, of the gill structure of a Xenopus laevis tadpole. The system sensitivity was measured to be 93 dB by using the prototype probe with an illumination power of 450 microW on the sample. Moreover, the axial and the lateral resolutions of the probe are 9.3 and 10.3-12.5 microm, respectively.

References

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Citations

Mar 7, 2014·The Review of Scientific Instruments·Hsuan-Chao HouM Feldman
May 10, 2008·Journal of Biomedical Optics·Shuo HanChanghuei Yang
Jul 5, 2011·Journal of Biomedical Optics·Vrushali R KordeJennifer K Barton
Oct 21, 2011·Annals of Biomedical Engineering·Danail Stoyanov
Jun 26, 2007·The Journal of Pain : Official Journal of the American Pain Society·David T RaphaelLinda Rever
Nov 21, 2014·Journal of Biophotonics·Shang Wang, Kirill V Larin
Nov 11, 2006·Lasers in Surgery and Medicine·Nigel R MunceI Alex Vitkin
Jan 11, 2007·Journal of Biomedical Optics·Zahid YaqoobChanghuei Yang
May 13, 2011·Analytical and Bioanalytical Chemistry·Julia WaltherEdmund Koch
Nov 27, 2014·Biomedical Optics Express·Shang Wang, Kirill V Larin
Oct 5, 2010·Optics Letters·Yi-Ying PuHe-Zhou Wang
Jun 27, 2015·Biomedical Optics Express·Ziwei Pang, Jigang Wu
Apr 30, 2014·Intravital·Hsing-Wen Wang, Yu Chen
Sep 7, 2013·Biomedical Optics Express·Karen M Joos, Jin-Hui Shen
Jul 1, 2017·Biomedical Optics Express·Michalina J GoraXingde Li

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