Palladium-Catalyzed Multicomponent Reaction of Alkynes, Carboxylic Acids, and Isocyanides: A Direct Approach to Captodative Olefins

Organic Letters
Mingchun GaoBin Xu

Abstract

A palladium-catalyzed multicomponent reaction of alkynes, carboxylic acids, and isocyanides has been developed with the assistance of silver salt under mild conditions. Highly functionalized captodative olefins are synthesized efficiently by this method, which can find many applications as versatile synthons in organic synthesis.

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Citations

Jun 26, 2020·Organic & Biomolecular Chemistry·Xu WangYing-Ming Pan

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