Palladium(II)-catalyzed oxidative C-H/C-H cross-coupling of heteroarenes

Journal of the American Chemical Society
Peihua XiJingsong You

Abstract

An efficient methodology for the synthesis of unsymmetrical biheteroaryl molecules has been developed via Pd(II)-catalyzed oxidative C-H/C-H cross-coupling of heteroarenes. An inversion in reactivity and selectivity has been achieved successfully to perform the desired heterocoupling. This process allows the heterocoupling of not only electron-rich N-containing heteroarenes (e.g., xanthines, azoles, and indolizines) but also electron-poor pyridine N-oxides with various thiophenes or furans.

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Citations

Aug 10, 2011·Journal of the American Chemical Society·Hien-Quang Do, Olafs Daugulis
Aug 13, 2011·Journal of the American Chemical Society·Xisheng WangJin-Quan Yu
Jan 5, 2011·The Journal of Organic Chemistry·Enrico T NadresOlafs Daugulis
Nov 5, 2010·Chemical Communications : Chem Comm·Dongbing ZhaoYing Xue
Mar 30, 2011·Chemical Communications : Chem Comm·Mikaël BrasseRobert G Bergman
Dec 10, 2015·Journal of the American Chemical Society·Xacobe C CambeiroIgor Larrosa
Jan 14, 2017·Chemical Reviews·Yudong YangJingsong You
Jul 28, 2016·Angewandte Chemie·Guangying TanJingsong You
May 20, 2014·Organic & Biomolecular Chemistry·Wen-Bing QinLiang-Xian Liu
Dec 5, 2014·Organic & Biomolecular Chemistry·K Anil KumarParthasarathi Das
Apr 27, 2017·Chemistry : a European Journal·Cristofer PezzettaGiovanni Poli
Sep 18, 2014·Chemical Communications : Chem Comm·Thomas E StorrMichael F Greaney
Mar 20, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Yong Liang, Stanislaw F Wnuk
Mar 11, 2015·Chemical Communications : Chem Comm·Dekun QinJingsong You
Jul 15, 2015·Chemical Communications : Chem Comm·Sheng ZhaoBing-Feng Shi
Jul 5, 2011·Angewandte Chemie·Jian Xiao, Xingwei Li
Apr 3, 2014·Chemistry : a European Journal·Maialen Espinal ViguriLucía Riera
Jul 19, 2012·Chemistry : a European Journal·Bo LiuJingsong You

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